Micafungin
Micafungin is an intravenous echinocandin antifungal medicine. It works by inhibiting the synthesis of beta-(1,3)-D-glucan, an essential component of the fungal cell wall, leading to osmotic instability and cell death in susceptible fungi, particularly Candida species.
Dosage by Body Weight
Administered only via intravenous infusion. Typical adult dose is 50 mg to 150 mg once daily depending on the indication. Pediatric dosage is calculated based on weight (typically 1 to 3 mg/kg daily, up to 4 to 10 mg/kg daily in neonates).
- Body Weight
- Below 5 kg
- Dose
- 4 to 10 mg/kg
- Frequency
- Once daily
- Tracking Notes
- Highly dependent on gestational age and infection type. Strictly administered under specialist supervision.
- Body Weight
- 5-7 kg
- Dose
- 10 to 21 mg (approx. 2-3 mg/kg)
- Frequency
- Once daily
- Tracking Notes
- Commonly used for systemic Candida infections or prophylaxis.
- Body Weight
- 8-10 kg
- Dose
- 16 to 30 mg (approx. 2-3 mg/kg)
- Frequency
- Once daily
- Tracking Notes
- Infuse intravenously over 1 hour. Do not mix with other medications.
- Body Weight
- 11-15 kg
- Dose
- 22 to 45 mg (approx. 2-3 mg/kg)
- Frequency
- Once daily
- Tracking Notes
- Dose may be increased up to 4 mg/kg if clinical response is inadequate.
- Body Weight
- 16-20 kg
- Dose
- 32 to 60 mg (approx. 2-3 mg/kg)
- Frequency
- Once daily
- Tracking Notes
- Do not exceed the maximum recommended adult dose of 150 mg/day.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 4 to 10 mg/kg | Once daily | Highly dependent on gestational age and infection type. Strictly administered under specialist supervision. |
| 5-7 kg | 10 to 21 mg (approx. 2-3 mg/kg) | Once daily | Commonly used for systemic Candida infections or prophylaxis. |
| 8-10 kg | 16 to 30 mg (approx. 2-3 mg/kg) | Once daily | Infuse intravenously over 1 hour. Do not mix with other medications. |
| 11-15 kg | 22 to 45 mg (approx. 2-3 mg/kg) | Once daily | Dose may be increased up to 4 mg/kg if clinical response is inadequate. |
| 16-20 kg | 32 to 60 mg (approx. 2-3 mg/kg) | Once daily | Do not exceed the maximum recommended adult dose of 150 mg/day. |
Formulation
Purpose
Treatment of invasive candidiasis, esophageal candidiasis, and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.
Generic Name
MicafunginBranded Drug Names
Micafungin is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.