Amphotericin B (Liposomal)
A potent antifungal. The liposomal version is much less toxic to the kidneys than the older 'deoxycholate' version. Used for severe systemic candida or aspergillus.
Dosage by Body Weight
Pediatric dose: 3 mg/kg to 5 mg/kg daily via IV infusion. Requires close monitoring of electrolytes and renal function.
- Body Weight
- 10-20 kg
- Dose
- 30 mg to 100 mg
- Frequency
- Once daily (IV)
- Tracking Notes
- Requires slow infusion (usually 2 hours) and hospital monitoring.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 10-20 kg | 30 mg to 100 mg | Once daily (IV) | Requires slow infusion (usually 2 hours) and hospital monitoring. |
Formulation
Purpose
Treatment of life-threatening fungal infections and Visceral Leishmaniasis (Kala-azar).
Generic Name
Liposomal Amphotericin BBranded Drug Names
Amphotericin B (Liposomal) is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONAmphotericin B (Liposomal): Alcohol may increase stomach upset and liver strain during antifungal therapy. Avoid or limit alcohol, especially with longer courses.
Pregnancy
CAUTIONAmphotericin B (Liposomal): Use in pregnancy only when prescribed; some antifungals are avoided unless the expected benefit clearly outweighs the risk.
Breast Feeding
SAFE IF PRESCRIBEDAmphotericin B (Liposomal): Use while breastfeeding only with healthcare provider guidance, especially for oral or systemic antifungals.
Driving
CAUTIONAmphotericin B (Liposomal): May cause dizziness, blurred vision, or headache in some people. Avoid driving if affected.
Liver
CAUTIONAmphotericin B (Liposomal): Can affect liver enzymes and may not be suitable in active liver disease without close monitoring.
Kidney
SAFE IF PRESCRIBEDAmphotericin B (Liposomal): Kidney impairment may require dose adjustment or monitoring for some antifungals. Use as prescribed.