Isonex
Isonex contains Isoniazid, a primary first-line antitubercular medication. It works by inhibiting the synthesis of mycolic acids, which are essential components of the bacterial cell wall of Mycobacterium tuberculosis, thereby leading to bacterial cell death.
Dosage by Body Weight
Take on an empty stomach, at least 1 hour before or 2 hours after meals, with a full glass of water. It is highly recommended to take Pyridoxine (Vitamin B6) concurrently to reduce the risk of peripheral neuropathy. Follow the exact duration prescribed by your healthcare provider to prevent drug resistance.
- Body Weight
- Below 5 kg
- Dose
- 10-15 mg/kg
- Frequency
- Once daily
- Tracking Notes
- Strictly under specialist pediatric supervision. Requires precise dosing using liquid formulations if available.
- Body Weight
- 5-7 kg
- Dose
- 50 mg to 75 mg
- Frequency
- Once daily
- Tracking Notes
- Dose calculated based on standard pediatric recommendation of 10-15 mg/kg per day.
- Body Weight
- 8-10 kg
- Dose
- 80 mg to 100 mg
- Frequency
- Once daily
- Tracking Notes
- Monitor liver function enzymes periodically during prolonged treatment.
- Body Weight
- 11-15 kg
- Dose
- 110 mg to 150 mg
- Frequency
- Once daily
- Tracking Notes
- Concomitant administration of Pyridoxine (Vitamin B6) is advised to prevent nerve issues.
- Body Weight
- 16-20 kg
- Dose
- 160 mg to 200 mg
- Frequency
- Once daily
- Tracking Notes
- Adjustments may be required if co-administered with other anti-TB medications.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 10-15 mg/kg | Once daily | Strictly under specialist pediatric supervision. Requires precise dosing using liquid formulations if available. |
| 5-7 kg | 50 mg to 75 mg | Once daily | Dose calculated based on standard pediatric recommendation of 10-15 mg/kg per day. |
| 8-10 kg | 80 mg to 100 mg | Once daily | Monitor liver function enzymes periodically during prolonged treatment. |
| 11-15 kg | 110 mg to 150 mg | Once daily | Concomitant administration of Pyridoxine (Vitamin B6) is advised to prevent nerve issues. |
| 16-20 kg | 160 mg to 200 mg | Once daily | Adjustments may be required if co-administered with other anti-TB medications. |
Formulation
Purpose
Treatment and prevention of active and latent Tuberculosis (TB) infections, typically used in combination with other anti-tubercular drugs.
Generic Name
IsoniazidScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.