Solonex
Solonex is an antibacterial prescription medicine containing Isoniazid, which belongs to the class of antitubercular agents. It works by interfering with the synthesis of mycolic acids, which are essential components of the bacterial cell wall in Mycobacterium tuberculosis, leading to bacterial cell death.
Dosage by Body Weight
Take on an empty stomach, at least 1 hour before or 2 hours after meals, for maximum absorption. Pyridoxine (Vitamin B6) supplementation is often recommended concurrently to prevent peripheral neuropathy, especially in patients with risk factors like malnutrition, diabetes, or alcoholism.
- Body Weight
- Below 5 kg
- Dose
- 10-15 mg/kg per day
- Frequency
- Once daily
- Tracking Notes
- Requires strict specialist pediatric supervision. Usually supplemented with Vitamin B6.
- Body Weight
- 5-7 kg
- Dose
- 50 mg to 100 mg daily
- Frequency
- Once daily
- Tracking Notes
- Administer on an empty stomach; monitor liver function tests regularly.
- Body Weight
- 8-10 kg
- Dose
- 80 mg to 150 mg daily
- Frequency
- Once daily
- Tracking Notes
- Adjust dosage precisely based on clinical response and tolerability.
- Body Weight
- 11-15 kg
- Dose
- 110 mg to 225 mg daily
- Frequency
- Once daily
- Tracking Notes
- Do not exceed pediatric limit guidelines; monitor for peripheral neuritis symptoms.
- Body Weight
- 16-20 kg
- Dose
- 160 mg to 300 mg daily
- Frequency
- Once daily
- Tracking Notes
- Do not exceed the maximum standard daily adult dose of 300 mg.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 10-15 mg/kg per day | Once daily | Requires strict specialist pediatric supervision. Usually supplemented with Vitamin B6. |
| 5-7 kg | 50 mg to 100 mg daily | Once daily | Administer on an empty stomach; monitor liver function tests regularly. |
| 8-10 kg | 80 mg to 150 mg daily | Once daily | Adjust dosage precisely based on clinical response and tolerability. |
| 11-15 kg | 110 mg to 225 mg daily | Once daily | Do not exceed pediatric limit guidelines; monitor for peripheral neuritis symptoms. |
| 16-20 kg | 160 mg to 300 mg daily | Once daily | Do not exceed the maximum standard daily adult dose of 300 mg. |
Formulation
Purpose
Used in the treatment of active tuberculosis (TB) infections in combination with other anti-tubercular medications, and for the prevention (prophylaxis) of tuberculosis in individuals at high risk of developing the disease.
Generic Name
IsoniazidScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.