Iso 300
Iso 300 contains Isoniazid 300mg, a primary antituberculosis medication. It interferes with lipid and nucleic acid biosynthesis in actively growing tubercle bacilli, rendering it highly effective against Mycobacterium tuberculosis.
Dosage by Body Weight
Take once daily on an empty stomach, either 1 hour before or 2 hours after meals. Often administered alongside Pyridoxine (Vitamin B6) to reduce the risk of peripheral neuropathy.
- Body Weight
- Below 5 kg
- Dose
- Not recommended using 300mg tablets
- Frequency
- Consult pediatrician
- Tracking Notes
- Requires pediatric-specific liquid or lower-strength dispersible formulations to ensure accurate dosing.
- Body Weight
- 5-7 kg
- Dose
- 50 mg to 70 mg daily
- Frequency
- Once daily
- Tracking Notes
- Splitting a 300mg tablet to this size is highly inaccurate; use 50mg or 100mg dispersible tablets instead.
- Body Weight
- 8-10 kg
- Dose
- 80 mg to 100 mg daily (approx. 1/3 tablet)
- Frequency
- Once daily
- Tracking Notes
- Use of pediatric-specific strengths (e.g., 100mg) is strongly recommended over splitting 300mg tablets.
- Body Weight
- 11-15 kg
- Dose
- 110 mg to 150 mg daily (approx. 1/2 tablet)
- Frequency
- Once daily
- Tracking Notes
- A 300mg tablet may be split into halves if scored, but pediatric formulations remain safer.
- Body Weight
- 16-20 kg
- Dose
- 160 mg to 200 mg daily (approx. 2/3 tablet)
- Frequency
- Once daily
- Tracking Notes
- Ensure regular monitoring of liver enzymes (AST/ALT) throughout the treatment course.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended using 300mg tablets | Consult pediatrician | Requires pediatric-specific liquid or lower-strength dispersible formulations to ensure accurate dosing. |
| 5-7 kg | 50 mg to 70 mg daily | Once daily | Splitting a 300mg tablet to this size is highly inaccurate; use 50mg or 100mg dispersible tablets instead. |
| 8-10 kg | 80 mg to 100 mg daily (approx. 1/3 tablet) | Once daily | Use of pediatric-specific strengths (e.g., 100mg) is strongly recommended over splitting 300mg tablets. |
| 11-15 kg | 110 mg to 150 mg daily (approx. 1/2 tablet) | Once daily | A 300mg tablet may be split into halves if scored, but pediatric formulations remain safer. |
| 16-20 kg | 160 mg to 200 mg daily (approx. 2/3 tablet) | Once daily | Ensure regular monitoring of liver enzymes (AST/ALT) throughout the treatment course. |
Formulation
Tablet
Purpose
Treatment and prevention of active and latent tuberculosis (TB) infections
Generic Name
IsoniazidBranded Drug Names
Iso 300 is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.