Theophylline
Works by relaxing airway smooth muscle and has mild anti-inflammatory properties. Narrow therapeutic window.
Dosage by Body Weight
Pediatric maintenance: 10-20 mg/kg/day divided. Titrate based on blood levels (goal 5-15 mcg/ml).
- Body Weight
- 20-40 kg
- Dose
- 100 mg to 200 mg
- Frequency
- Twice daily (Extended release)
- Tracking Notes
- Do not crush extended-release tablets.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 20-40 kg | 100 mg to 200 mg | Twice daily (Extended release) | Do not crush extended-release tablets. |
Formulation
Purpose
Maintenance therapy for chronic asthma and apnea of prematurity.
Generic Name
TheophyllineBranded Drug Names
Theophylline is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONTheophylline: Alcohol may worsen palpitations, dizziness, dehydration, or breathing control. Avoid or limit alcohol if symptoms occur.
Pregnancy
SAFE IF PRESCRIBEDTheophylline: Use during pregnancy only when prescribed; controlling breathing or pulmonary pressure problems may be essential.
Breast Feeding
SAFE IF PRESCRIBEDTheophylline: Use while breastfeeding only as directed; inhaled treatments are often preferred when suitable.
Driving
CAUTIONTheophylline: May cause tremor, dizziness, headache, or palpitations. Avoid driving if you feel unwell.
Liver
CAUTIONTheophylline: Use with healthcare guidance in significant liver disease or when long-term monitoring is required.
Kidney
CAUTIONTheophylline: Use caution in kidney disease, especially if electrolyte changes or blood pressure effects are possible.