Racigyl
Racigyl contains Racecadotril, an oral prodrug of thiorphan, which is an enkephalinase inhibitor. It exhibits selective antidiarrheal action by reducing intestinal hypersecretion of water and electrolytes without affecting basal secretion or prolonging intestinal transit time. It is typically used alongside oral rehydration therapy.
Dosage by Body Weight
Should be administered orally, usually three times daily, preferably before meals. For infants and children, sachets are dissolved in water or mixed with food/milk. Treatment should be continued until two normal stools are recorded, not exceeding 7 days.
- Body Weight
- Below 5 kg
- Dose
- Not routinely recommended
- Frequency
- Use only if prescribed by a specialist
- Tracking Notes
- Safety and efficacy in infants under 3 months or below 5 kg have not been established.
- Body Weight
- 5-7 kg
- Dose
- 10 mg (1 sachet of Racigyl 10)
- Frequency
- Three times daily
- Tracking Notes
- To be given along with oral rehydration salts (ORS) to prevent dehydration.
- Body Weight
- 8-10 kg
- Dose
- 10 mg (1 sachet of Racigyl 10)
- Frequency
- Three times daily
- Tracking Notes
- Administer at regular intervals. Can be mixed directly with baby food or formula.
- Body Weight
- 11-15 kg
- Dose
- 30 mg (1 sachet of Racigyl 30)
- Frequency
- Three times daily
- Tracking Notes
- Ensure adequate fluid intake. Do not exceed the recommended duration of 7 days.
- Body Weight
- 16-20 kg
- Dose
- 30 mg (1 sachet of Racigyl 30)
- Frequency
- Three times daily
- Tracking Notes
- Consult a doctor if diarrhea persists beyond 48 to 72 hours despite treatment.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routinely recommended | Use only if prescribed by a specialist | Safety and efficacy in infants under 3 months or below 5 kg have not been established. |
| 5-7 kg | 10 mg (1 sachet of Racigyl 10) | Three times daily | To be given along with oral rehydration salts (ORS) to prevent dehydration. |
| 8-10 kg | 10 mg (1 sachet of Racigyl 10) | Three times daily | Administer at regular intervals. Can be mixed directly with baby food or formula. |
| 11-15 kg | 30 mg (1 sachet of Racigyl 30) | Three times daily | Ensure adequate fluid intake. Do not exceed the recommended duration of 7 days. |
| 16-20 kg | 30 mg (1 sachet of Racigyl 30) | Three times daily | Consult a doctor if diarrhea persists beyond 48 to 72 hours despite treatment. |
Formulation
Purpose
Used for the symptomatic treatment of acute diarrhea in adults and children. It acts as an antisecretory drug by inhibiting enkephalinase, thereby reducing the excessive secretion of water and electrolytes into the intestine.
Generic Name
RacecadotrilScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.