Cadotril
Cadotril contains Racecadotril, which is an oral enkephalinase inhibitor (antidiarrheal). It works by reducing the hypersecretion of water and electrolytes in the intestines without affecting basal secretion or delaying intestinal transit time.
Dosage by Body Weight
Should be taken three times daily, preferably before meals. Treatment should be continued until two normal stools are recorded, up to a maximum of 7 days. It must be co-administered with abundant oral rehydration therapy.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy in infants under 3 months of age or weighing less than 5 kg have not been established.
- Body Weight
- 5-7 kg
- Dose
- 10 mg
- Frequency
- Three times daily
- Tracking Notes
- Administer as pediatric sachets or suspension mixed with food or dissolved in water.
- Body Weight
- 8-10 kg
- Dose
- 10 mg to 15 mg
- Frequency
- Three times daily
- Tracking Notes
- Standard pediatric dose is calculated at approximately 1.5 mg/kg per dose.
- Body Weight
- 11-15 kg
- Dose
- 30 mg
- Frequency
- Three times daily
- Tracking Notes
- Typically administered as one 30 mg sachet per dose.
- Body Weight
- 16-20 kg
- Dose
- 30 mg
- Frequency
- Three times daily
- Tracking Notes
- Administered as one 30 mg sachet per dose. For children weighing over 27 kg, the dose may be increased to 60 mg three times daily under medical supervision.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy in infants under 3 months of age or weighing less than 5 kg have not been established. |
| 5-7 kg | 10 mg | Three times daily | Administer as pediatric sachets or suspension mixed with food or dissolved in water. |
| 8-10 kg | 10 mg to 15 mg | Three times daily | Standard pediatric dose is calculated at approximately 1.5 mg/kg per dose. |
| 11-15 kg | 30 mg | Three times daily | Typically administered as one 30 mg sachet per dose. |
| 16-20 kg | 30 mg | Three times daily | Administered as one 30 mg sachet per dose. For children weighing over 27 kg, the dose may be increased to 60 mg three times daily under medical supervision. |
Formulation
Purpose
Used for the symptomatic treatment of acute diarrhea in adults and children (administered alongside oral rehydration).
Generic Name
RacecadotrilScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.