Privigen
Privigen is a ready-to-use, sterile, liquid preparation of highly purified immunoglobulin G (IgG) antibodies derived from human plasma. It is used to replace missing antibodies in patients with primary immunodeficiency diseases or to help regulate immune responses in inflammatory and autoimmune disorders.
Dosage by Body Weight
Privigen must be administered intravenously by a healthcare professional. Dosage is highly individualized and calculated based on the patient's body weight and specific clinical indication (typically ranging from 200 mg/kg to 2 g/kg).
- Body Weight
- Below 5 kg
- Dose
- 200 to 800 mg per kg
- Frequency
- Every 3 to 4 weeks for PI; daily for 2-5 days for ITP
- Tracking Notes
- Must be calculated individually by a specialist. Start infusion at a very low rate.
- Body Weight
- 5-7 kg
- Dose
- 200 to 800 mg per kg
- Frequency
- Every 3 to 4 weeks for PI; daily for 2-5 days for ITP
- Tracking Notes
- Infusion rate and volume must be strictly monitored to avoid fluid overload.
- Body Weight
- 8-10 kg
- Dose
- 200 to 800 mg per kg
- Frequency
- Every 3 to 4 weeks for PI; daily for 2-5 days for ITP
- Tracking Notes
- Dosing interval may be adjusted based on clinical response and trough IgG levels.
- Body Weight
- 11-15 kg
- Dose
- 200 to 800 mg per kg
- Frequency
- Every 3 to 4 weeks for PI; daily for 2-5 days for ITP
- Tracking Notes
- Dose adjustment should be based on therapeutic clinical response.
- Body Weight
- 16-20 kg
- Dose
- 200 to 800 mg per kg
- Frequency
- Every 3 to 4 weeks for PI; daily for 2-5 days for ITP
- Tracking Notes
- Administer under the supervision of a physician experienced in managing immunoglobulins.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 200 to 800 mg per kg | Every 3 to 4 weeks for PI; daily for 2-5 days for ITP | Must be calculated individually by a specialist. Start infusion at a very low rate. |
| 5-7 kg | 200 to 800 mg per kg | Every 3 to 4 weeks for PI; daily for 2-5 days for ITP | Infusion rate and volume must be strictly monitored to avoid fluid overload. |
| 8-10 kg | 200 to 800 mg per kg | Every 3 to 4 weeks for PI; daily for 2-5 days for ITP | Dosing interval may be adjusted based on clinical response and trough IgG levels. |
| 11-15 kg | 200 to 800 mg per kg | Every 3 to 4 weeks for PI; daily for 2-5 days for ITP | Dose adjustment should be based on therapeutic clinical response. |
| 16-20 kg | 200 to 800 mg per kg | Every 3 to 4 weeks for PI; daily for 2-5 days for ITP | Administer under the supervision of a physician experienced in managing immunoglobulins. |
Formulation
Purpose
Treatment of Primary Immunodeficiency (PI), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), and Chronic Immune Thrombocytopenia (ITP).
Generic Name
Immune Globulin Intravenous (Human), 10% LiquidScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.