Gamunex-C
Gamunex-C is a sterile, ready-to-use solution of human immune globulin (IgG) containing 10% protein. It is purified from pooled human plasma and provides broad-spectrum IgG antibodies to protect against infections and modulate immune responses in autoimmune conditions.
Dosage by Body Weight
Dosage must be individualized based on the specific indication, patient's weight, and clinical response. Standard dosing ranges from 300-600 mg/kg every 3 to 4 weeks for PI, and up to 2 g/kg total dose for ITP or CIDP. Administered via intravenous (IV) or subcutaneous (SC) infusion.
- Body Weight
- Below 5 kg
- Dose
- 1.5 g to 3 g (calculated at 300-600 mg/kg for PI)
- Frequency
- Every 3 to 4 weeks
- Tracking Notes
- Infusion rate must be strictly monitored. Highly subject to specialist prescription and oversight.
- Body Weight
- 5-7 kg
- Dose
- 1.5 g to 4.2 g (calculated at 300-600 mg/kg for PI)
- Frequency
- Every 3 to 4 weeks
- Tracking Notes
- Subcutaneous dosing may require administration across multiple infusion sites.
- Body Weight
- 8-10 kg
- Dose
- 2.4 g to 6 g (calculated at 300-600 mg/kg for PI)
- Frequency
- Every 3 to 4 weeks
- Tracking Notes
- For ITP, standard acute dosing is significantly higher (typically 1 g/kg to 2 g/kg).
- Body Weight
- 11-15 kg
- Dose
- 3.3 g to 9 g (calculated at 300-600 mg/kg for PI)
- Frequency
- Every 3 to 4 weeks
- Tracking Notes
- Ensure patient is adequately hydrated prior to initiating administration to minimize renal risks.
- Body Weight
- 16-20 kg
- Dose
- 4.8 g to 12 g (calculated at 300-600 mg/kg for PI)
- Frequency
- Every 3 to 4 weeks
- Tracking Notes
- Dosing should be calculated based on actual body weight at the time of prescription.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 1.5 g to 3 g (calculated at 300-600 mg/kg for PI) | Every 3 to 4 weeks | Infusion rate must be strictly monitored. Highly subject to specialist prescription and oversight. |
| 5-7 kg | 1.5 g to 4.2 g (calculated at 300-600 mg/kg for PI) | Every 3 to 4 weeks | Subcutaneous dosing may require administration across multiple infusion sites. |
| 8-10 kg | 2.4 g to 6 g (calculated at 300-600 mg/kg for PI) | Every 3 to 4 weeks | For ITP, standard acute dosing is significantly higher (typically 1 g/kg to 2 g/kg). |
| 11-15 kg | 3.3 g to 9 g (calculated at 300-600 mg/kg for PI) | Every 3 to 4 weeks | Ensure patient is adequately hydrated prior to initiating administration to minimize renal risks. |
| 16-20 kg | 4.8 g to 12 g (calculated at 300-600 mg/kg for PI) | Every 3 to 4 weeks | Dosing should be calculated based on actual body weight at the time of prescription. |
Formulation
Purpose
Used to treat Primary Humoral Immunodeficiency (PI), Idiopathic Thrombocytopenic Purpura (ITP), and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP).
Generic Name
Immune Globulin Intravenous (Human), 10% LiquidScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.