Gammagard
Gammagard is a sterile, purified preparation of human immunoglobulin G (IgG) antibodies. It provides therapeutic antibodies to help prevent infections in patients with weakened immune systems and to treat certain autoimmune neurological conditions.
Dosage by Body Weight
Dosage is highly individualized and must be calculated based on the specific indication, patient's body weight, and clinical response. Typically administered intravenously (IV) or subcutaneously (SC). Standard primary immunodeficiency dosage is 300 to 600 mg/kg body weight administered every 3 to 4 weeks for IV, or weekly for SC.
- Body Weight
- Below 5 kg
- Dose
- 300 - 600 mg/kg (calculated per patient weight)
- Frequency
- Every 3 to 4 weeks (IV) or weekly (SC)
- Tracking Notes
- Infusion rate must start very slow. Strict clinical monitoring is required.
- Body Weight
- 5-7 kg
- Dose
- 300 - 600 mg/kg (calculated per patient weight)
- Frequency
- Every 3 to 4 weeks (IV) or weekly (SC)
- Tracking Notes
- Adjust dose based on clinical response and serum IgG trough levels.
- Body Weight
- 8-10 kg
- Dose
- 300 - 600 mg/kg (calculated per patient weight)
- Frequency
- Every 3 to 4 weeks (IV) or weekly (SC)
- Tracking Notes
- Administer under the supervision of a healthcare provider.
- Body Weight
- 11-15 kg
- Dose
- 300 - 600 mg/kg (calculated per patient weight)
- Frequency
- Every 3 to 4 weeks (IV) or weekly (SC)
- Tracking Notes
- Ensure adequate hydration prior to beginning the infusion.
- Body Weight
- 16-20 kg
- Dose
- 300 - 600 mg/kg (calculated per patient weight)
- Frequency
- Every 3 to 4 weeks (IV) or weekly (SC)
- Tracking Notes
- Monitor vital signs and for any adverse reactions throughout the infusion.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 300 - 600 mg/kg (calculated per patient weight) | Every 3 to 4 weeks (IV) or weekly (SC) | Infusion rate must start very slow. Strict clinical monitoring is required. |
| 5-7 kg | 300 - 600 mg/kg (calculated per patient weight) | Every 3 to 4 weeks (IV) or weekly (SC) | Adjust dose based on clinical response and serum IgG trough levels. |
| 8-10 kg | 300 - 600 mg/kg (calculated per patient weight) | Every 3 to 4 weeks (IV) or weekly (SC) | Administer under the supervision of a healthcare provider. |
| 11-15 kg | 300 - 600 mg/kg (calculated per patient weight) | Every 3 to 4 weeks (IV) or weekly (SC) | Ensure adequate hydration prior to beginning the infusion. |
| 16-20 kg | 300 - 600 mg/kg (calculated per patient weight) | Every 3 to 4 weeks (IV) or weekly (SC) | Monitor vital signs and for any adverse reactions throughout the infusion. |
Formulation
Purpose
Used as replacement therapy for primary immunodeficiency (PI) in adults and pediatric patients, and as maintenance therapy to improve muscle strength and disability in adult patients with Multifocal Motor Neuropathy (MMN).
Generic Name
Immune Globulin Infusion (Human)Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.