Prepidil
Prepidil is a local endocervical gel containing dinoprostone, a naturally occurring prostaglandin E2 (PGE2). It is used to prepare, soften, and dilate (ripen) the cervix prior to the induction of labor in pregnant women at or near term.
Dosage by Body Weight
Administered strictly by a healthcare professional in a hospital setting. The standard dose is 0.5 mg (one syringe of 2.5 mL gel) inserted into the cervical canal. If there is insufficient cervical response, a repeat dose of 0.5 mg can be administered after 6 hours, up to a maximum of 1.5 mg (3 doses) within a 24-hour period.
- Body Weight
- Below 5 kg
- Dose
- Contraindicated
- Frequency
- Not applicable
- Tracking Notes
- Not for pediatric use. Indicated only for pregnant adult females at term.
- Body Weight
- 5-7 kg
- Dose
- Contraindicated
- Frequency
- Not applicable
- Tracking Notes
- Not for pediatric use. Indicated only for pregnant adult females at term.
- Body Weight
- 8-10 kg
- Dose
- Contraindicated
- Frequency
- Not applicable
- Tracking Notes
- Not for pediatric use. Indicated only for pregnant adult females at term.
- Body Weight
- 11-15 kg
- Dose
- Contraindicated
- Frequency
- Not applicable
- Tracking Notes
- Not for pediatric use. Indicated only for pregnant adult females at term.
- Body Weight
- 16-20 kg
- Dose
- Contraindicated
- Frequency
- Not applicable
- Tracking Notes
- Not for pediatric use. Indicated only for pregnant adult females at term.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Contraindicated | Not applicable | Not for pediatric use. Indicated only for pregnant adult females at term. |
| 5-7 kg | Contraindicated | Not applicable | Not for pediatric use. Indicated only for pregnant adult females at term. |
| 8-10 kg | Contraindicated | Not applicable | Not for pediatric use. Indicated only for pregnant adult females at term. |
| 11-15 kg | Contraindicated | Not applicable | Not for pediatric use. Indicated only for pregnant adult females at term. |
| 16-20 kg | Contraindicated | Not applicable | Not for pediatric use. Indicated only for pregnant adult females at term. |
Formulation
Purpose
Cervical ripening in pregnant women at or near term with a medical or obstetric need for labor induction.
Generic Name
DinoprostoneScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.