Misoprostol
Misoprostol is a synthetic prostaglandin E1 analog that protects the gastric mucosa by inhibiting basal and nocturnal gastric acid secretion, and by increasing bicarbonate and mucus production. It also causes uterine contractions and is widely used in obstetric and gynecological procedures.
Dosage by Body Weight
Dosage depends strictly on the medical indication. For ulcer prevention, a typical adult dose is 200 mcg four times daily with food. For obstetric uses, specific strict clinical protocols must be followed under medical supervision. This medication is not indicated for routine pediatric use.
- Body Weight
- Below 5 kg
- Dose
- Not established
- Frequency
- Not recommended
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
- Body Weight
- 5-7 kg
- Dose
- Not established
- Frequency
- Not recommended
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
- Body Weight
- 8-10 kg
- Dose
- Not established
- Frequency
- Not recommended
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
- Body Weight
- 11-15 kg
- Dose
- Not established
- Frequency
- Not recommended
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
- Body Weight
- 16-20 kg
- Dose
- Not established
- Frequency
- Not recommended
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not established | Not recommended | Safety and efficacy in pediatric patients have not been established. |
| 5-7 kg | Not established | Not recommended | Safety and efficacy in pediatric patients have not been established. |
| 8-10 kg | Not established | Not recommended | Safety and efficacy in pediatric patients have not been established. |
| 11-15 kg | Not established | Not recommended | Safety and efficacy in pediatric patients have not been established. |
| 16-20 kg | Not established | Not recommended | Safety and efficacy in pediatric patients have not been established. |
Formulation
Purpose
Prevention of NSAID-induced gastric ulcers, medical abortion (typically in combination with mifepristone), induction of labor, and management of postpartum hemorrhage.
Generic Name
MisoprostolBranded Drug Names
Misoprostol is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.