Midazolam (Buccal/Nasal)

A fast-acting benzodiazepine. The buccal form is applied to the side of the mouth (between gums and cheek) for rapid absorption into the bloodstream.

Dosage by Body Weight

Dose is age and weight-based. Typically 0.2 mg/kg to 0.5 mg/kg. Only use as directed by a neurologist in emergencies.

Body Weight
5-10 kg
Dose
2.5 mg
Frequency
Single dose (Emergency)
Tracking Notes
If seizure doesn't stop in 5-10 mins, call emergency services.
Body Weight
11-20 kg
Dose
5 mg
Frequency
Single dose (Emergency)
Tracking Notes
Monitor for respiratory depression.

Weight-based dosage tracking table for Midazolam (Buccal/Nasal), including body weight, dose, frequency, and tracking notes.
Body Weight	Dose	Frequency	Tracking Notes
5-10 kg	2.5 mg	Single dose (Emergency)	If seizure doesn't stop in 5-10 mins, call emergency services.
11-20 kg	5 mg	Single dose (Emergency)	Monitor for respiratory depression.

Formulation

Oral SolutionNasal SprayInjection

Purpose

Rescue medication for prolonged acute convulsive seizures (Status Epilepticus).

Generic Name

Midazolam

Branded Drug Names

Midazolam (Buccal/Nasal) is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Diazepam (Rectal)

Safety Advice

Alcohol

UNSAFE

Midazolam (Buccal/Nasal): Alcohol can significantly increase drowsiness, dizziness, breathing problems, or seizure risk. Avoid alcohol unless a specialist says otherwise.

Pregnancy

CAUTION

Midazolam (Buccal/Nasal): Use in pregnancy only under specialist advice because seizure control and fetal risks must be carefully balanced.

Breast Feeding

SAFE IF PRESCRIBED

Midazolam (Buccal/Nasal): May pass into breast milk and can cause infant drowsiness or feeding issues. Use only with healthcare provider guidance.

Driving

CAUTION

Midazolam (Buccal/Nasal): Can cause drowsiness, slowed reaction time, dizziness, or blurred vision. Avoid driving until you know how it affects you.

Liver

CAUTION

Midazolam (Buccal/Nasal): Some anti-seizure medicines can affect liver function and may require blood tests or dose adjustments.

Kidney

CAUTION

Midazolam (Buccal/Nasal): Some anti-seizure medicines require dose adjustment in kidney impairment. Use under medical supervision.