Nayzilam
Nayzilam is a benzodiazepine nasal spray containing midazolam, used as a rescue medication for the short-term treatment of seizure clusters in patients 12 years of age and older.
Dosage by Body Weight
Administer one spray (5 mg) into one nostril. A second dose (5 mg) may be administered into the opposite nostril after 10 minutes if the seizure has not stopped, or if another seizure occurs. Do not administer more than 2 doses for a single episode. Do not treat more than 1 episode every 3 days or more than 5 episodes per month.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Nayzilam is not indicated for pediatric patients under 12 years of age.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and effectiveness have not been established in patients younger than 12 years.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and effectiveness have not been established in patients younger than 12 years.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and effectiveness have not been established in patients younger than 12 years.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and effectiveness have not been established in patients younger than 12 years.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Do not use | Nayzilam is not indicated for pediatric patients under 12 years of age. |
| 5-7 kg | Not recommended | Do not use | Safety and effectiveness have not been established in patients younger than 12 years. |
| 8-10 kg | Not recommended | Do not use | Safety and effectiveness have not been established in patients younger than 12 years. |
| 11-15 kg | Not recommended | Do not use | Safety and effectiveness have not been established in patients younger than 12 years. |
| 16-20 kg | Not recommended | Do not use | Safety and effectiveness have not been established in patients younger than 12 years. |
Formulation
Purpose
Acute treatment of intermittent, stereotypic episodes of frequent seizure activity (i.e., seizure clusters, acute repetitive seizures) that are distinct from a patient's usual seizure pattern in patients with epilepsy 12 years of age and older.
Generic Name
MidazolamScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.