Leucovorin Calcium
Leucovorin Calcium (folinic acid) is an active metabolite of folic acid. It acts as an antidote to folic acid antagonists like methotrexate and is also used to enhance the therapeutic effects of 5-fluorouracil in cancer treatments.
Dosage by Body Weight
Dosage is strictly determined by a physician. In methotrexate rescue, administration depends on body surface area (BSA) and serum methotrexate levels, rather than simple body weight.
- Body Weight
- Below 5 kg
- Dose
- Strictly individualized
- Frequency
- As directed by oncologist
- Tracking Notes
- Dosing is calculated using Body Surface Area (BSA) and monitored methotrexate levels. Not for routine use.
- Body Weight
- 5-7 kg
- Dose
- Strictly individualized
- Frequency
- As directed by oncologist
- Tracking Notes
- Requires calculation based on Body Surface Area (BSA) and clinical monitoring.
- Body Weight
- 8-10 kg
- Dose
- Strictly individualized
- Frequency
- As directed by oncologist
- Tracking Notes
- Requires calculation based on Body Surface Area (BSA) and clinical monitoring.
- Body Weight
- 11-15 kg
- Dose
- Strictly individualized
- Frequency
- As directed by oncologist
- Tracking Notes
- Requires calculation based on Body Surface Area (BSA) and clinical monitoring.
- Body Weight
- 16-20 kg
- Dose
- Strictly individualized
- Frequency
- As directed by oncologist
- Tracking Notes
- Requires calculation based on Body Surface Area (BSA) and clinical monitoring.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Strictly individualized | As directed by oncologist | Dosing is calculated using Body Surface Area (BSA) and monitored methotrexate levels. Not for routine use. |
| 5-7 kg | Strictly individualized | As directed by oncologist | Requires calculation based on Body Surface Area (BSA) and clinical monitoring. |
| 8-10 kg | Strictly individualized | As directed by oncologist | Requires calculation based on Body Surface Area (BSA) and clinical monitoring. |
| 11-15 kg | Strictly individualized | As directed by oncologist | Requires calculation based on Body Surface Area (BSA) and clinical monitoring. |
| 16-20 kg | Strictly individualized | As directed by oncologist | Requires calculation based on Body Surface Area (BSA) and clinical monitoring. |
Formulation
Purpose
Used to prevent or decrease toxic effects of methotrexate (methotrexate rescue) and to treat certain types of anemia or colorectal cancer in combination therapy.
Generic Name
Leucovorin CalciumBranded Drug Names
Leucovorin Calcium is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.