Lamez
Lamez contains Lamotrigine, an anticonvulsant medication. It works by stabilizing hyper-excited nerve membranes and inhibiting the pathological release of glutamate, an excitatory neurotransmitter. It is primarily used to prevent depressive episodes in bipolar disorder and control various types of epileptic seizures.
Dosage by Body Weight
Dosage must be strictly individualized. It is typically started at a very low dose (e.g., 25 mg daily or every other day) and gradually escalated over several weeks to reduce the risk of a severe, potentially life-threatening skin rash (Stevens-Johnson syndrome). Do not stop taking this medication abruptly.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Avoid use
- Tracking Notes
- Safety and efficacy in infants have not been established.
- Body Weight
- 5-7 kg
- Dose
- Highly individualized (typically starting at 0.15 to 0.6 mg/kg/day)
- Frequency
- Once daily or alternate days
- Tracking Notes
- Dosing depends heavily on concurrent medications (such as Valproate or Carbamazepine). Use dispersible tablets for precise dosing.
- Body Weight
- 8-10 kg
- Dose
- Highly individualized (typically starting at 1.25 mg to 5 mg daily)
- Frequency
- Once daily or alternate days
- Tracking Notes
- Must be titrated slowly. Monitor closely for skin rashes, fever, or swollen glands.
- Body Weight
- 11-15 kg
- Dose
- Highly individualized (typically starting at 2 mg to 7.5 mg daily)
- Frequency
- Once daily or divided into two doses
- Tracking Notes
- Adjustment is critical if co-administered with hepatic enzyme-inducing or inhibiting drugs.
- Body Weight
- 16-20 kg
- Dose
- Highly individualized (typically starting at 2.5 mg to 10 mg daily)
- Frequency
- Once daily or divided into two doses
- Tracking Notes
- Ensure parents/caregivers are fully aware of the warning signs of serious hypersensitivity reactions.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Avoid use | Safety and efficacy in infants have not been established. |
| 5-7 kg | Highly individualized (typically starting at 0.15 to 0.6 mg/kg/day) | Once daily or alternate days | Dosing depends heavily on concurrent medications (such as Valproate or Carbamazepine). Use dispersible tablets for precise dosing. |
| 8-10 kg | Highly individualized (typically starting at 1.25 mg to 5 mg daily) | Once daily or alternate days | Must be titrated slowly. Monitor closely for skin rashes, fever, or swollen glands. |
| 11-15 kg | Highly individualized (typically starting at 2 mg to 7.5 mg daily) | Once daily or divided into two doses | Adjustment is critical if co-administered with hepatic enzyme-inducing or inhibiting drugs. |
| 16-20 kg | Highly individualized (typically starting at 2.5 mg to 10 mg daily) | Once daily or divided into two doses | Ensure parents/caregivers are fully aware of the warning signs of serious hypersensitivity reactions. |
Formulation
Purpose
Used for the treatment of epilepsy (to control seizures) and as a mood stabilizer in bipolar disorder.
Generic Name
LamotrigineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.