Lametec
Lametec contains Lamotrigine, an anticonvulsant medicine that works by decreasing abnormal electrical activity in the brain. It is used either alone or with other medications to prevent and control seizures. It is also used to delay mood episodes in adults with bipolar disorder.
Dosage by Body Weight
Dosage must be strictly individualized and titrated slowly over several weeks to minimize the risk of serious skin rashes, such as Stevens-Johnson syndrome. Do not stop taking this medication abruptly.
- Body Weight
- Below 5 kg
- Dose
- Safety and efficacy not established
- Frequency
- Not recommended
- Tracking Notes
- Consult a pediatric neurologist for alternative therapies.
- Body Weight
- 5-7 kg
- Dose
- 0.15 mg/kg to 0.6 mg/kg daily starting dose
- Frequency
- Once daily or divided twice daily
- Tracking Notes
- Dose depends heavily on whether patient is also taking valproate or enzyme-inducing drugs.
- Body Weight
- 8-10 kg
- Dose
- 1.2 mg to 6 mg daily starting dose
- Frequency
- Once daily or divided twice daily
- Tracking Notes
- Titrated slowly over weeks. Use dispersible/soluble tablets for precise pediatric dosing.
- Body Weight
- 11-15 kg
- Dose
- 1.65 mg to 9 mg daily starting dose
- Frequency
- Once daily or divided twice daily
- Tracking Notes
- Requires strict titration schedules to avoid serious cutaneous adverse reactions.
- Body Weight
- 16-20 kg
- Dose
- 2.4 mg to 12 mg daily starting dose
- Frequency
- Once daily or divided twice daily
- Tracking Notes
- Maintenance doses will be higher after standard 6-week titration protocol.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Safety and efficacy not established | Not recommended | Consult a pediatric neurologist for alternative therapies. |
| 5-7 kg | 0.15 mg/kg to 0.6 mg/kg daily starting dose | Once daily or divided twice daily | Dose depends heavily on whether patient is also taking valproate or enzyme-inducing drugs. |
| 8-10 kg | 1.2 mg to 6 mg daily starting dose | Once daily or divided twice daily | Titrated slowly over weeks. Use dispersible/soluble tablets for precise pediatric dosing. |
| 11-15 kg | 1.65 mg to 9 mg daily starting dose | Once daily or divided twice daily | Requires strict titration schedules to avoid serious cutaneous adverse reactions. |
| 16-20 kg | 2.4 mg to 12 mg daily starting dose | Once daily or divided twice daily | Maintenance doses will be higher after standard 6-week titration protocol. |
Formulation
TabletDispersible Tablet
Purpose
Used in the treatment of epilepsy (seizures) and clinically as a mood stabilizer for bipolar disorder to prevent depressive episodes.
Generic Name
LamotrigineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.