Lamotrigine
Works by inhibiting voltage-sensitive sodium channels. Requires a very slow 'start low, go slow' titration to prevent severe rashes (Stevens-Johnson Syndrome).
Dosage by Body Weight
Initial dose is usually 0.15 mg/kg once daily for 2 weeks, then increased. Dosage depends on whether the child is also taking valproate.
- Body Weight
- 20-40 kg
- Dose
- 5 mg to 25 mg (Initial)
- Frequency
- Once daily
- Tracking Notes
- Discontinue immediately if any skin rash develops.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 20-40 kg | 5 mg to 25 mg (Initial) | Once daily | Discontinue immediately if any skin rash develops. |
Formulation
Purpose
Antiepileptic and mood stabilizer.
Generic Name
LamotrigineBranded Drug Names
Lamotrigine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
UNSAFELamotrigine: Alcohol can significantly increase drowsiness, dizziness, breathing problems, or seizure risk. Avoid alcohol unless a specialist says otherwise.
Pregnancy
CAUTIONLamotrigine: Use in pregnancy only under specialist advice because seizure control and fetal risks must be carefully balanced.
Breast Feeding
SAFE IF PRESCRIBEDLamotrigine: May pass into breast milk and can cause infant drowsiness or feeding issues. Use only with healthcare provider guidance.
Driving
CAUTIONLamotrigine: Can cause drowsiness, slowed reaction time, dizziness, or blurred vision. Avoid driving until you know how it affects you.
Liver
CAUTIONLamotrigine: Some anti-seizure medicines can affect liver function and may require blood tests or dose adjustments.
Kidney
CAUTIONLamotrigine: Some anti-seizure medicines require dose adjustment in kidney impairment. Use under medical supervision.