Topiramate
Has multiple mechanisms: blocks sodium channels, enhances GABA activity, and antagonizes glutamate receptors.
Dosage by Body Weight
For epilepsy: Initial 1-3 mg/kg/night. Titrate weekly. Encourage fluid intake to prevent kidney stones.
- Body Weight
- 10-20 kg
- Dose
- 25 mg to 50 mg total daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- May cause decreased sweating and overheating (hypohidrosis).
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 10-20 kg | 25 mg to 50 mg total daily | Divided into 2 doses | May cause decreased sweating and overheating (hypohidrosis). |
Formulation
Sprinkle CapsuleTablet
Purpose
Antiepileptic and migraine prophylaxis.
Generic Name
Topiramate
Branded Drug Names
Topiramate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
- Topamax
- Topirol
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
ValproateLevetiracetam