Ethambutol Hydrochloride
Ethambutol Hydrochloride is an oral bacteriostatic antimycobacterial agent. It is specifically active against actively growing mycobacteria of the genus Mycobacterium, including M. tuberculosis. It functions by inhibiting the synthesis of arabinogalactan, an essential component of the mycobacterial cell wall.
Dosage by Body Weight
Administered orally once every 24 hours. The standard dose is calculated based on body weight, typically ranging from 15 mg/kg to 25 mg/kg per day. Frequent assessment of visual acuity and color discrimination is highly recommended during therapy.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Not routinely recommended due to difficulties in monitoring pediatric visual acuity and ocular toxicity in infants.
- Body Weight
- 5-7 kg
- Dose
- 75 mg to 150 mg
- Frequency
- Once daily
- Tracking Notes
- Approximate range based on 15-25 mg/kg/day standard pediatric dosing. Use under strict medical supervision.
- Body Weight
- 8-10 kg
- Dose
- 120 mg to 200 mg
- Frequency
- Once daily
- Tracking Notes
- Approximate range based on 15-25 mg/kg/day. Monitor hepatic and visual functions regularly.
- Body Weight
- 11-15 kg
- Dose
- 165 mg to 300 mg
- Frequency
- Once daily
- Tracking Notes
- Approximate range based on 15-25 mg/kg/day. Adjust dose based on regular weight monitoring.
- Body Weight
- 16-20 kg
- Dose
- 240 mg to 400 mg
- Frequency
- Once daily
- Tracking Notes
- Approximate range based on 15-25 mg/kg/day. Adult and pediatric doses must be strictly calibrated.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Not routinely recommended due to difficulties in monitoring pediatric visual acuity and ocular toxicity in infants. |
| 5-7 kg | 75 mg to 150 mg | Once daily | Approximate range based on 15-25 mg/kg/day standard pediatric dosing. Use under strict medical supervision. |
| 8-10 kg | 120 mg to 200 mg | Once daily | Approximate range based on 15-25 mg/kg/day. Monitor hepatic and visual functions regularly. |
| 11-15 kg | 165 mg to 300 mg | Once daily | Approximate range based on 15-25 mg/kg/day. Adjust dose based on regular weight monitoring. |
| 16-20 kg | 240 mg to 400 mg | Once daily | Approximate range based on 15-25 mg/kg/day. Adult and pediatric doses must be strictly calibrated. |
Formulation
Purpose
Used in combination with other antituberculosis medications for the treatment of active pulmonary and extra-pulmonary tuberculosis (TB).
Generic Name
Ethambutol HydrochlorideBranded Drug Names
Ethambutol Hydrochloride is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.