Isoniazid
Works by inhibiting the synthesis of mycolic acids, an essential component of the bacterial cell wall in Mycobacteria.
Dosage by Body Weight
Pediatric dose: 10 mg/kg (range 7-15 mg/kg) once daily. Often prescribed with Pyridoxine (Vitamin B6) to prevent nerve damage.
- Body Weight
- 5-7 kg
- Dose
- 50 mg to 75 mg
- Frequency
- Once daily
- Tracking Notes
- Administer with Vitamin B6 supplement daily.
- Body Weight
- 8-12 kg
- Dose
- 100 mg
- Frequency
- Once daily
- Tracking Notes
- Report any signs of yellow eyes or skin (jaundice) immediately.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 5-7 kg | 50 mg to 75 mg | Once daily | Administer with Vitamin B6 supplement daily. |
| 8-12 kg | 100 mg | Once daily | Report any signs of yellow eyes or skin (jaundice) immediately. |
Formulation
Purpose
First-line treatment and prevention (prophylaxis) of Tuberculosis.
Generic Name
Isoniazid (INH)Branded Drug Names
Isoniazid is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONIsoniazid: Alcohol may increase dizziness, stomach upset, dehydration, or other side effects. Avoid or limit alcohol and follow medical advice.
Pregnancy
SAFE IF PRESCRIBEDIsoniazid: Use during pregnancy only if prescribed after a healthcare provider weighs the benefits and risks.
Breast Feeding
SAFE IF PRESCRIBEDIsoniazid: Use while breastfeeding only with healthcare provider guidance, especially for repeated or long-term treatment.
Driving
CAUTIONIsoniazid: This medicine may cause dizziness, drowsiness, weakness, or blurred vision in some people. Avoid driving if affected.
Liver
CAUTIONIsoniazid: Use with caution in liver disease and consult your healthcare provider if you have abnormal liver tests or jaundice.
Kidney
CAUTIONIsoniazid: Use with caution in kidney disease because dose adjustment or monitoring may be needed for some patients.