Pyrazinamide
A key component of short-course TB therapy. It is specifically active against bacteria residing in acidic environments like macrophages.
Dosage by Body Weight
Pediatric dose: 30-40 mg/kg once daily for the first 2 months of TB treatment.
- Body Weight
- 5-7 kg
- Dose
- 250 mg
- Frequency
- Once daily
- Tracking Notes
- Monitor liver function tests and uric acid levels.
- Body Weight
- 8-12 kg
- Dose
- 400 mg
- Frequency
- Once daily
- Tracking Notes
- May cause joint pain (arthralgia).
- Body Weight
- 13-18 kg
- Dose
- 600 mg
- Frequency
- Once daily
- Tracking Notes
- Usually given as part of a Fixed Dose Combination (FDC).
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 5-7 kg | 250 mg | Once daily | Monitor liver function tests and uric acid levels. |
| 8-12 kg | 400 mg | Once daily | May cause joint pain (arthralgia). |
| 13-18 kg | 600 mg | Once daily | Usually given as part of a Fixed Dose Combination (FDC). |
Formulation
Tablet
Purpose
Anti-tuberculosis medication used in the initial phase of treatment.
Generic Name
Pyrazinamide
Branded Drug Names
Pyrazinamide is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
- Pyzina
- PZA
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.