Sulfasalazine

A combination of an antibiotic (sulfapyridine) and an anti-inflammatory (5-ASA). It reduces inflammation in the colon and joints.

Dosage by Body Weight

Pediatric JIA: 30-50 mg/kg/day divided into 2 doses. Start low to minimize GI side effects.

  1. Body Weight
    20-30 kg
    Dose
    500 mg
    Frequency
    Twice daily
    Tracking Notes
    Swallow tablets whole. Monitor CBC and liver function.

Formulation

TabletDelayed-release Tablet

Purpose

Treatment of Ulcerative Colitis and Juvenile Rheumatoid Arthritis.

Generic Name

Sulfasalazine

Branded Drug Names

Sulfasalazine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

CAUTION

Sulfasalazine: Alcohol can worsen stomach irritation, dehydration, dizziness, or bowel symptoms. Avoid or limit alcohol.

Pregnancy

SAFE IF PRESCRIBED

Sulfasalazine: Use during pregnancy only when prescribed or recommended by a healthcare provider for the specific condition.

Breast Feeding

SAFE IF PRESCRIBED

Sulfasalazine: Use while breastfeeding only as directed; monitor the infant for diarrhea, drowsiness, or feeding changes when relevant.

Driving

SAFE

Sulfasalazine: Usually does not affect driving, but dizziness, cramps, or weakness can occur. Avoid driving if affected.

Liver

CAUTION

Sulfasalazine: Use caution in significant liver disease or when the medicine is used for liver-related complications.

Kidney

CAUTION

Sulfasalazine: Kidney disease or dehydration can increase side-effect risk for some gastrointestinal medicines. Use with medical guidance.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.