Mesalamine (5-ASA)
A local anti-inflammatory that works directly on the lining of the gut to reduce the symptoms of IBD.
Dosage by Body Weight
Pediatric dose: 30-50 mg/kg/day for active disease. Maintenance is usually lower.
- Body Weight
- 20-40 kg
- Dose
- 500 mg to 1000 mg
- Frequency
- Two times daily
- Tracking Notes
- Delayed-release tablets must not be crushed or chewed.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 20-40 kg | 500 mg to 1000 mg | Two times daily | Delayed-release tablets must not be crushed or chewed. |
Formulation
Purpose
Treatment of Inflammatory Bowel Disease (IBD) such as Ulcerative Colitis.
Generic Name
MesalazineBranded Drug Names
Mesalamine (5-ASA) is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONMesalamine (5-ASA): Alcohol can worsen stomach irritation, dehydration, dizziness, or bowel symptoms. Avoid or limit alcohol.
Pregnancy
SAFE IF PRESCRIBEDMesalamine (5-ASA): Use during pregnancy only when prescribed or recommended by a healthcare provider for the specific condition.
Breast Feeding
SAFE IF PRESCRIBEDMesalamine (5-ASA): Use while breastfeeding only as directed; monitor the infant for diarrhea, drowsiness, or feeding changes when relevant.
Driving
SAFEMesalamine (5-ASA): Usually does not affect driving, but dizziness, cramps, or weakness can occur. Avoid driving if affected.
Liver
CAUTIONMesalamine (5-ASA): Use caution in significant liver disease or when the medicine is used for liver-related complications.
Kidney
CAUTIONMesalamine (5-ASA): Kidney disease or dehydration can increase side-effect risk for some gastrointestinal medicines. Use with medical guidance.