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Methotrexate

At low doses for JIA, it acts as an anti-inflammatory and immune modulator. **Dosed ONCE WEEKLY only**.

Dosage by Body Weight

Standard JIA dose: 10–15 mg/m² (approx 0.5 mg/kg) **ONCE PER WEEK**. Give with Folic Acid to reduce mouth sores.

  1. Body Weight
    15-25 kg
    Dose
    7.5 mg to 12.5 mg
    Frequency
    Once weekly
    Tracking Notes
    Verify the weekly schedule; daily dosing can be fatal.

Formulation

TabletInjection

Purpose

Treatment of Juvenile Idiopathic Arthritis (JIA) and certain pediatric cancers.

Generic Name

Methotrexate

Branded Drug Names

Methotrexate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

  • Rheumatrex
  • Mexate

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

LeflunomideSulfasalazine

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.