Itraconazole
Inhibits fungal cytochrome P450-dependent enzymes, preventing the synthesis of ergosterol. The oral solution is better absorbed and preferred for pediatric patients.
Dosage by Body Weight
Pediatric dose: 3-5 mg/kg/day. Capsules must be taken with a full meal; oral solution is taken on an empty stomach.
- Body Weight
- 10-20 kg
- Dose
- 50 mg to 100 mg
- Frequency
- Once daily
- Tracking Notes
- Monitor liver enzymes for prolonged courses.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 10-20 kg | 50 mg to 100 mg | Once daily | Monitor liver enzymes for prolonged courses. |
Formulation
Purpose
Broad-spectrum antifungal for systemic and superficial fungal infections.
Generic Name
ItraconazoleBranded Drug Names
Itraconazole is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONItraconazole: Alcohol may increase stomach upset and liver strain during antifungal therapy. Avoid or limit alcohol, especially with longer courses.
Pregnancy
CAUTIONItraconazole: Use in pregnancy only when prescribed; some antifungals are avoided unless the expected benefit clearly outweighs the risk.
Breast Feeding
SAFE IF PRESCRIBEDItraconazole: Use while breastfeeding only with healthcare provider guidance, especially for oral or systemic antifungals.
Driving
CAUTIONItraconazole: May cause dizziness, blurred vision, or headache in some people. Avoid driving if affected.
Liver
CAUTIONItraconazole: Can affect liver enzymes and may not be suitable in active liver disease without close monitoring.
Kidney
SAFE IF PRESCRIBEDItraconazole: Kidney impairment may require dose adjustment or monitoring for some antifungals. Use as prescribed.