Canditral
Canditral is an antifungal medication containing Itraconazole, belonging to the triazole class. It works by inhibiting the fungal cytochrome P450-mediated synthesis of ergosterol, a vital component of the fungal cell membrane, which disrupts membrane integrity and stops fungal growth.
Dosage by Body Weight
Canditral capsules must be taken immediately after a full meal to ensure maximum absorption. Do not crush, break, or chew the capsules. Complete the entire course of treatment as prescribed by your doctor, even if symptoms clear up earlier. Do not take antacids within 2 hours of taking this medication.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Strictly as prescribed
- Tracking Notes
- Safety and efficacy in infants weighing less than 5 kg have not been established. Use only under direct specialist supervision.
- Body Weight
- 5-7 kg
- Dose
- 15 mg to 35 mg (calculated at 3-5 mg/kg)
- Frequency
- Once daily
- Tracking Notes
- Liquid formulation (oral solution) is preferred for accurate pediatric dosing. Monitor liver function during prolonged use.
- Body Weight
- 8-10 kg
- Dose
- 24 mg to 50 mg
- Frequency
- Once daily
- Tracking Notes
- Dosage should be strictly determined by a pediatrician based on the severity of the infection.
- Body Weight
- 11-15 kg
- Dose
- 33 mg to 75 mg
- Frequency
- Once daily
- Tracking Notes
- Capsules should not be opened or mixed with food; use oral solution if the child cannot swallow capsules.
- Body Weight
- 16-20 kg
- Dose
- 50 mg to 100 mg
- Frequency
- Once daily
- Tracking Notes
- Must be taken with a full meal. Dose adjustments may be required for systemic infections.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Strictly as prescribed | Safety and efficacy in infants weighing less than 5 kg have not been established. Use only under direct specialist supervision. |
| 5-7 kg | 15 mg to 35 mg (calculated at 3-5 mg/kg) | Once daily | Liquid formulation (oral solution) is preferred for accurate pediatric dosing. Monitor liver function during prolonged use. |
| 8-10 kg | 24 mg to 50 mg | Once daily | Dosage should be strictly determined by a pediatrician based on the severity of the infection. |
| 11-15 kg | 33 mg to 75 mg | Once daily | Capsules should not be opened or mixed with food; use oral solution if the child cannot swallow capsules. |
| 16-20 kg | 50 mg to 100 mg | Once daily | Must be taken with a full meal. Dose adjustments may be required for systemic infections. |
Formulation
Purpose
Treatment of systemic and superficial fungal infections, including blastomycosis, histoplasmosis, aspergillosis, vulvovaginal candidiasis, and dermatophytoses like ringworm, tinea versicolor, and athlete's foot.
Generic Name
ItraconazoleScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.