Sporanox
Sporanox is an azole antifungal prescription medication that works by preventing the growth of fungal organisms. It targets the synthesis of ergosterol, a vital component of fungal cell membranes, leading to membrane instability and cell death.
Dosage by Body Weight
Dosage must be individualized. Sporanox capsules must be taken immediately after a full meal to ensure optimal absorption, whereas Sporanox oral solution should be taken on an empty stomach. Standard adult dosing ranges from 100 mg to 400 mg daily depending on the infection type.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in infants and pediatric patients in this weight class.
- Body Weight
- 5-7 kg
- Dose
- 3 to 5 mg/kg daily
- Frequency
- Once daily
- Tracking Notes
- Must be determined and monitored strictly by a pediatric specialist. Use of oral solution is typically preferred for exact measurement.
- Body Weight
- 8-10 kg
- Dose
- 3 to 5 mg/kg daily
- Frequency
- Once daily
- Tracking Notes
- Requires exact calculation by a physician. Periodic liver function tests may be recommended.
- Body Weight
- 11-15 kg
- Dose
- 33 mg to 75 mg
- Frequency
- Once daily
- Tracking Notes
- Calculated based on 3-5 mg/kg/day target. Use liquid formulation for precise dosing.
- Body Weight
- 16-20 kg
- Dose
- 50 mg to 100 mg
- Frequency
- Once daily
- Tracking Notes
- Dose depends heavily on the severity and site of the fungal infection. Do not exceed adult maximums.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in infants and pediatric patients in this weight class. |
| 5-7 kg | 3 to 5 mg/kg daily | Once daily | Must be determined and monitored strictly by a pediatric specialist. Use of oral solution is typically preferred for exact measurement. |
| 8-10 kg | 3 to 5 mg/kg daily | Once daily | Requires exact calculation by a physician. Periodic liver function tests may be recommended. |
| 11-15 kg | 33 mg to 75 mg | Once daily | Calculated based on 3-5 mg/kg/day target. Use liquid formulation for precise dosing. |
| 16-20 kg | 50 mg to 100 mg | Once daily | Dose depends heavily on the severity and site of the fungal infection. Do not exceed adult maximums. |
Formulation
Purpose
Treatment of systemic fungal infections including blastomycosis, histoplasmosis, and aspergillosis, as well as superficial fungal infections like onychomycosis (nail fungus) and oropharyngeal/esophageal candidiasis.
Generic Name
ItraconazoleScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.