Domperidone

Domperidone increases movements or contractions of the stomach and bowel. It also blocks dopamine receptors in the brain to reduce nausea.

Dosage by Body Weight

Use in children is restricted in some regions due to cardiac risk. Dosage must be strictly weight-based (0.25 mg/kg up to 3 times daily).

  1. Body Weight
    5-10 kg
    Dose
    1.25-2.5 mg
    Frequency
    Up to 3 times daily
    Tracking Notes
    Administer 15-30 minutes before food.
  2. Body Weight
    11-20 kg
    Dose
    2.75-5 mg
    Frequency
    Up to 3 times daily
    Tracking Notes
    Use the lowest effective dose for the shortest duration.

Formulation

TabletSuspensionDrops

Purpose

Antiemetic and prokinetic agent used to treat nausea and vomiting, and to increase breast milk production (off-label).

Generic Name

Domperidone

Branded Drug Names

Domperidone is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

CAUTION

Alcohol may increase dizziness or heart rhythm concerns with domperidone. Avoid alcohol unless your healthcare provider says it is safe.

Pregnancy

CAUTION

Domperidone should be used during pregnancy only when clearly prescribed, as safety data are limited and cardiac risks must be considered.

Breast Feeding

CAUTION

Domperidone can pass into breast milk and is sometimes used off-label for lactation, but it carries cardiac risk. Use only under medical supervision.

Driving

SAFE

Domperidone usually has minimal effect on alertness, but dizziness can occur. Avoid driving if you feel dizzy or faint.

Liver

CAUTION

Domperidone is not recommended in moderate to severe liver impairment due to increased risk of side effects.

Kidney

CAUTION

Domperidone may require reduced dosing frequency in kidney impairment. Use only with healthcare provider guidance.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.