Docetaxel
Docetaxel is a clinically well-established anti-mitotic chemotherapy medication. It belongs to the taxane drug class and works by stabilizing microtubules, preventing their disassembly, which halts cell division and leads to cancer cell death.
Dosage by Body Weight
Docetaxel is administered exclusively via intravenous infusion under the supervision of a qualified oncologist. Dosing is highly individualized and calculated based on the patient's Body Surface Area (BSA) in mg/m² (typically 60-100 mg/m² given every 3 weeks) rather than simple body weight. Premedication with oral corticosteroids is routinely required to prevent severe hypersensitivity reactions and fluid retention.
- Body Weight
- Below 5 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Pediatric safety and effectiveness have not been established.
- Body Weight
- 5-7 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Pediatric safety and effectiveness have not been established.
- Body Weight
- 8-10 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Pediatric safety and effectiveness have not been established.
- Body Weight
- 11-15 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Pediatric safety and effectiveness have not been established.
- Body Weight
- 16-20 kg
- Dose
- Not established
- Frequency
- Not applicable
- Tracking Notes
- Pediatric safety and effectiveness have not been established.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not established | Not applicable | Pediatric safety and effectiveness have not been established. |
| 5-7 kg | Not established | Not applicable | Pediatric safety and effectiveness have not been established. |
| 8-10 kg | Not established | Not applicable | Pediatric safety and effectiveness have not been established. |
| 11-15 kg | Not established | Not applicable | Pediatric safety and effectiveness have not been established. |
| 16-20 kg | Not established | Not applicable | Pediatric safety and effectiveness have not been established. |
Formulation
Purpose
Treatment of breast cancer, non-small cell lung cancer, prostate cancer, gastric adenocarcinoma, and squamous cell carcinoma of the head and neck.
Generic Name
DocetaxelBranded Drug Names
Docetaxel is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.