Paclitaxel
Paclitaxel is a taxane-class chemotherapy medication that works by stabilizing microtubules and interfering with the normal breakdown of microtubules during cell division, thereby halting cell replication and inducing cancer cell death.
Dosage by Body Weight
Paclitaxel is administered intravenously under the supervision of a qualified oncologist. Dosage is highly individualized and calculated based on Body Surface Area (BSA) in mg/m², rather than direct body weight. Premedication with corticosteroids, H1 antagonists, and H2 antagonists is required prior to infusion to prevent severe hypersensitivity reactions.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Pediatric dosing requires specialized calculation based on Body Surface Area (BSA) by a pediatric oncologist.
- Body Weight
- 5-7 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Requires strict, individual calculations based on BSA and clinical protocol.
- Body Weight
- 8-10 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Must be calculated by a specialist; not standardly dosed by weight alone.
- Body Weight
- 11-15 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Oncology-specific dosing protocols apply.
- Body Weight
- 16-20 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Oncology-specific dosing protocols apply.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Pediatric dosing requires specialized calculation based on Body Surface Area (BSA) by a pediatric oncologist. |
| 5-7 kg | Not routine | Use only if prescribed | Requires strict, individual calculations based on BSA and clinical protocol. |
| 8-10 kg | Not routine | Use only if prescribed | Must be calculated by a specialist; not standardly dosed by weight alone. |
| 11-15 kg | Not routine | Use only if prescribed | Oncology-specific dosing protocols apply. |
| 16-20 kg | Not routine | Use only if prescribed | Oncology-specific dosing protocols apply. |
Formulation
Purpose
Used as a chemotherapeutic agent to treat breast cancer, ovarian cancer, non-small cell lung cancer (NSCLC), and AIDS-related Kaposi's sarcoma.
Generic Name
PaclitaxelBranded Drug Names
Paclitaxel is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.