Arteether
Arteether (also known as artether) is a rapid-acting blood schizonticide and a semi-synthetic derivative of artemisinin. It is specifically formulated as an injectable antimalarial drug indicated for the treatment of severe malaria, including cerebral malaria caused by Plasmodium falciparum. It operates by releasing free radicals within the parasite's food vacuole, leading to lipid peroxidation and cellular damage.
Dosage by Body Weight
Administered strictly via deep intramuscular injection. The typical adult dosage is 150 mg once daily for 3 consecutive days. For pediatric cases, it is calculated based on body weight, usually 3 mg/kg once daily for 3 days.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy in infants under 5 kg have not been established.
- Body Weight
- 5-7 kg
- Dose
- 15 mg to 21 mg (3 mg/kg)
- Frequency
- Once daily for 3 days
- Tracking Notes
- To be given only via deep intramuscular injection under clinical supervision.
- Body Weight
- 8-10 kg
- Dose
- 24 mg to 30 mg (3 mg/kg)
- Frequency
- Once daily for 3 days
- Tracking Notes
- To be given only via deep intramuscular injection under clinical supervision.
- Body Weight
- 11-15 kg
- Dose
- 33 mg to 45 mg (3 mg/kg)
- Frequency
- Once daily for 3 days
- Tracking Notes
- To be given only via deep intramuscular injection under clinical supervision.
- Body Weight
- 16-20 kg
- Dose
- 48 mg to 60 mg (3 mg/kg)
- Frequency
- Once daily for 3 days
- Tracking Notes
- To be given only via deep intramuscular injection under clinical supervision.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy in infants under 5 kg have not been established. |
| 5-7 kg | 15 mg to 21 mg (3 mg/kg) | Once daily for 3 days | To be given only via deep intramuscular injection under clinical supervision. |
| 8-10 kg | 24 mg to 30 mg (3 mg/kg) | Once daily for 3 days | To be given only via deep intramuscular injection under clinical supervision. |
| 11-15 kg | 33 mg to 45 mg (3 mg/kg) | Once daily for 3 days | To be given only via deep intramuscular injection under clinical supervision. |
| 16-20 kg | 48 mg to 60 mg (3 mg/kg) | Once daily for 3 days | To be given only via deep intramuscular injection under clinical supervision. |
Formulation
Purpose
Treatment of severe falciparum malaria, including cerebral malaria, and chloroquine-resistant malaria cases.
Generic Name
ArteetherBranded Drug Names
Arteether is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.