Rapither
Rapither is an antimalarial injection containing Alpha-Beta Arteether, a semi-synthetic artemisinin derivative. It is specifically used for the treatment of severe and complicated malaria, including cerebral malaria, typically when oral administration is not feasible.
Dosage by Body Weight
Administered exclusively via deep intramuscular injection (IM). The standard adult dosage is 150 mg once daily for 3 consecutive days. Pediatric dosage is calculated at 3 mg/kg body weight once daily for 3 consecutive days.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy in infants weighing less than 5 kg have not been established.
- Body Weight
- 5-7 kg
- Dose
- 15 mg to 21 mg (approx. 0.2 mL to 0.28 mL of 150mg/2mL strength) once daily for 3 days
- Frequency
- Once daily
- Tracking Notes
- Must be administered deep intramuscularly by a qualified healthcare professional.
- Body Weight
- 8-10 kg
- Dose
- 24 mg to 30 mg (approx. 0.32 mL to 0.4 mL of 150mg/2mL strength) once daily for 3 days
- Frequency
- Once daily
- Tracking Notes
- Must be administered deep intramuscularly by a qualified healthcare professional.
- Body Weight
- 11-15 kg
- Dose
- 33 mg to 45 mg (approx. 0.44 mL to 0.6 mL of 150mg/2mL strength) once daily for 3 days
- Frequency
- Once daily
- Tracking Notes
- Must be administered deep intramuscularly by a qualified healthcare professional.
- Body Weight
- 16-20 kg
- Dose
- 48 mg to 60 mg (approx. 0.64 mL to 0.8 mL of 150mg/2mL strength) once daily for 3 days
- Frequency
- Once daily
- Tracking Notes
- Must be administered deep intramuscularly by a qualified healthcare professional.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy in infants weighing less than 5 kg have not been established. |
| 5-7 kg | 15 mg to 21 mg (approx. 0.2 mL to 0.28 mL of 150mg/2mL strength) once daily for 3 days | Once daily | Must be administered deep intramuscularly by a qualified healthcare professional. |
| 8-10 kg | 24 mg to 30 mg (approx. 0.32 mL to 0.4 mL of 150mg/2mL strength) once daily for 3 days | Once daily | Must be administered deep intramuscularly by a qualified healthcare professional. |
| 11-15 kg | 33 mg to 45 mg (approx. 0.44 mL to 0.6 mL of 150mg/2mL strength) once daily for 3 days | Once daily | Must be administered deep intramuscularly by a qualified healthcare professional. |
| 16-20 kg | 48 mg to 60 mg (approx. 0.64 mL to 0.8 mL of 150mg/2mL strength) once daily for 3 days | Once daily | Must be administered deep intramuscularly by a qualified healthcare professional. |
Formulation
Injection
Purpose
Treatment of severe malaria, including cerebral malaria, and chloroquine-resistant malaria caused by Plasmodium falciparum.
Generic Name
Alpha-Beta ArteetherScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.