Terbina
Terbina is an allylamine antifungal medication. It works by inhibiting the enzyme squalene epoxidase, which is essential for fungal cell membrane synthesis. This leads to a deficiency of ergosterol and an accumulation of squalene inside the fungal cell, causing cell death.
Dosage by Body Weight
For adults, the standard oral dosage is 250 mg once daily. The duration of treatment depends on the type and severity of the infection (typically 2 to 6 weeks for skin infections, and 6 to 12 weeks for nail infections). In children, oral terbinafine is primarily prescribed for tinea capitis (scalp ringworm) for patients aged 2 years and older, with the dose determined by body weight.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy have not been established in children of this weight range.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy have not been established.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy have not been established.
- Body Weight
- 11-15 kg
- Dose
- 62.5 mg
- Frequency
- Once daily
- Tracking Notes
- Only for pediatric patients aged 2 years and older. Usually administered as one-fourth of a 250 mg tablet.
- Body Weight
- 16-20 kg
- Dose
- 125 mg
- Frequency
- Once daily
- Tracking Notes
- Suitable for children weighing 15 to 25 kg. Usually administered as half of a 250 mg tablet.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Use only if prescribed | Safety and efficacy have not been established in children of this weight range. |
| 5-7 kg | Not recommended | Use only if prescribed | Safety and efficacy have not been established. |
| 8-10 kg | Not recommended | Use only if prescribed | Safety and efficacy have not been established. |
| 11-15 kg | 62.5 mg | Once daily | Only for pediatric patients aged 2 years and older. Usually administered as one-fourth of a 250 mg tablet. |
| 16-20 kg | 125 mg | Once daily | Suitable for children weighing 15 to 25 kg. Usually administered as half of a 250 mg tablet. |
Formulation
Purpose
Used to treat various fungal infections of the skin and nails, including athlete's foot (tinea pedis), jock itch (tinea cruris), ringworm (tinea corporis), and fungal nail infections (onychomycosis).
Generic Name
TerbinafineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.