Sebifin
Sebifin is an antifungal medication containing Terbinafine Hydrochloride. It belongs to the allylamine class of antifungals and works by inhibiting squalene epoxidase, a key enzyme in fungal cell membrane synthesis, leading to ergosterol deficiency and intracellular squalene accumulation, causing fungal cell death.
Dosage by Body Weight
For adults, the typical oral dose is 250 mg once daily. The duration of treatment varies from 2 to 6 weeks for skin infections (like tinea pedis or corporis) and 6 weeks to 12 weeks for nail infections (onychomycosis). It should be taken exactly as prescribed by a healthcare professional and the course must be completed even if symptoms improve.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in this weight range.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Oral terbinafine is generally not prescribed for children in this weight or age group.
- Body Weight
- 8-10 kg
- Dose
- Not routinely recommended
- Frequency
- N/A
- Tracking Notes
- Consult a pediatrician. Only used if benefits outweigh risks and specifically prescribed.
- Body Weight
- 11-15 kg
- Dose
- 62.5 mg to 125 mg
- Frequency
- Once daily
- Tracking Notes
- For children over 2 years of age. Pediatric dosing must be carefully monitored by a physician.
- Body Weight
- 16-20 kg
- Dose
- 125 mg
- Frequency
- Once daily
- Tracking Notes
- Typically prescribed for tinea capitis (scalp ringworm) in children weighing less than 25 kg.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in this weight range. |
| 5-7 kg | Not recommended | N/A | Oral terbinafine is generally not prescribed for children in this weight or age group. |
| 8-10 kg | Not routinely recommended | N/A | Consult a pediatrician. Only used if benefits outweigh risks and specifically prescribed. |
| 11-15 kg | 62.5 mg to 125 mg | Once daily | For children over 2 years of age. Pediatric dosing must be carefully monitored by a physician. |
| 16-20 kg | 125 mg | Once daily | Typically prescribed for tinea capitis (scalp ringworm) in children weighing less than 25 kg. |
Formulation
Purpose
Used to treat fungal infections of the skin, scalp, and nails, such as ringworm, athlete's foot, jock itch, and tinea unguium (nail fungal infection).
Generic Name
TerbinafineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.