Tadalafil
Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor. It aids in erectile dysfunction by relaxing smooth muscles and increasing blood flow to the corpus cavernosum, and helps in PAH by dilating the pulmonary vascular bed.
Dosage by Body Weight
For ED (on-demand): 10 mg to 20 mg taken prior to anticipated sexual activity. For ED (daily use) or BPH: 2.5 mg to 5 mg once daily. For PAH: 40 mg once daily. Avoid use with nitrates.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in this weight group.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in this weight group.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in this weight group.
- Body Weight
- 11-15 kg
- Dose
- Not routinely used
- Frequency
- Use only if prescribed
- Tracking Notes
- Pediatric dosing for PAH is highly specialized and must be determined by a specialist.
- Body Weight
- 16-20 kg
- Dose
- Not routinely used
- Frequency
- Use only if prescribed
- Tracking Notes
- Pediatric dosing for PAH is highly specialized and must be determined by a specialist.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in this weight group. |
| 5-7 kg | Not recommended | N/A | Safety and efficacy have not been established in this weight group. |
| 8-10 kg | Not recommended | N/A | Safety and efficacy have not been established in this weight group. |
| 11-15 kg | Not routinely used | Use only if prescribed | Pediatric dosing for PAH is highly specialized and must be determined by a specialist. |
| 16-20 kg | Not routinely used | Use only if prescribed | Pediatric dosing for PAH is highly specialized and must be determined by a specialist. |
Formulation
Purpose
Used to treat erectile dysfunction (ED), symptoms of benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension (PAH).
Generic Name
TadalafilBranded Drug Names
Tadalafil is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.