Reltone
Reltone is a prescription bile acid (ursodiol) used to dissolve gallstones and prevent their formation in high-risk patients. It works by decreasing the amount of cholesterol in the bile, helping to dissolve cholesterol-based stones.
Dosage by Body Weight
Standard adult dose for gallstone dissolution is 8-10 mg/kg/day divided into 2-3 doses, taken with food. For gallstone prevention during weight loss, the dose is typically 300 mg twice daily.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established for routine use. Specialist supervision required.
- Body Weight
- 5-7 kg
- Dose
- 40 mg to 70 mg daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- Requires compounded oral liquid formulation. Use strictly under pediatric specialist guidance.
- Body Weight
- 8-10 kg
- Dose
- 64 mg to 100 mg daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- Requires liquid formulation or pharmacy compounding for accurate dosing.
- Body Weight
- 11-15 kg
- Dose
- 88 mg to 150 mg daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- Compounded oral suspension is recommended for precise administration.
- Body Weight
- 16-20 kg
- Dose
- 128 mg to 200 mg daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- A 200 mg capsule may be used if appropriate under direct medical advice, or compounded suspension.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy in pediatric patients have not been established for routine use. Specialist supervision required. |
| 5-7 kg | 40 mg to 70 mg daily | Divided into 2 doses | Requires compounded oral liquid formulation. Use strictly under pediatric specialist guidance. |
| 8-10 kg | 64 mg to 100 mg daily | Divided into 2 doses | Requires liquid formulation or pharmacy compounding for accurate dosing. |
| 11-15 kg | 88 mg to 150 mg daily | Divided into 2 doses | Compounded oral suspension is recommended for precise administration. |
| 16-20 kg | 128 mg to 200 mg daily | Divided into 2 doses | A 200 mg capsule may be used if appropriate under direct medical advice, or compounded suspension. |
Formulation
Capsule
Purpose
Dissolving cholesterol gallstones in patients who are not candidates for surgery, and preventing gallstone formation in patients experiencing rapid weight loss.
Generic Name
UrsodiolScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.