Primacin
Primacin contains Primaquine, an antimalarial medication that targets the tissue/liver stages (hypnozoites) of Plasmodium vivax and Plasmodium ovale to prevent relapse. It is also used to prevent transmission of Plasmodium falciparum. Due to the risk of severe hemolytic anemia, G6PD deficiency screening is mandatory for all patients prior to initiating therapy.
Dosage by Body Weight
Strictly follow the physician's prescription. Standard adult dose is 15 mg base daily for 14 days. Pediatric dosing is based on weight (typically 0.25 mg/kg to 0.5 mg/kg base once daily for 14 days). Should be taken with food to reduce gastrointestinal side effects.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Contraindicated in infants under 6 months or under 5 kg. Extremely high risk of toxicity.
- Body Weight
- 5-7 kg
- Dose
- 1.25 mg to 2.5 mg
- Frequency
- Once daily for 14 days
- Tracking Notes
- Dosage based on 0.25 to 0.5 mg/kg. Requires careful division of tablets. G6PD test is mandatory before starting.
- Body Weight
- 8-10 kg
- Dose
- 2.0 mg to 3.75 mg
- Frequency
- Once daily for 14 days
- Tracking Notes
- Administer strictly under pediatric supervision with food to avoid gastric irritation.
- Body Weight
- 11-15 kg
- Dose
- 2.75 mg to 5.6 mg
- Frequency
- Once daily for 14 days
- Tracking Notes
- Monitor closely for signs of hemolysis (dark urine, fatigue, jaundice).
- Body Weight
- 16-20 kg
- Dose
- 4.0 mg to 7.5 mg
- Frequency
- Once daily for 14 days
- Tracking Notes
- 7.5 mg is approximately equivalent to one half-strength pediatric tablet. Ensure strict compliance for the full 14-day course.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Do not use | Contraindicated in infants under 6 months or under 5 kg. Extremely high risk of toxicity. |
| 5-7 kg | 1.25 mg to 2.5 mg | Once daily for 14 days | Dosage based on 0.25 to 0.5 mg/kg. Requires careful division of tablets. G6PD test is mandatory before starting. |
| 8-10 kg | 2.0 mg to 3.75 mg | Once daily for 14 days | Administer strictly under pediatric supervision with food to avoid gastric irritation. |
| 11-15 kg | 2.75 mg to 5.6 mg | Once daily for 14 days | Monitor closely for signs of hemolysis (dark urine, fatigue, jaundice). |
| 16-20 kg | 4.0 mg to 7.5 mg | Once daily for 14 days | 7.5 mg is approximately equivalent to one half-strength pediatric tablet. Ensure strict compliance for the full 14-day course. |
Formulation
Purpose
Radical cure and prevention of relapse in Plasmodium vivax and Plasmodium ovale malaria, and terminal prophylaxis of malaria.
Generic Name
PrimaquineScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.