Prami
Prami contains Pramipexole, a dopamine agonist. It works by stimulating dopamine receptors in the brain, helping to improve muscle control, reduce tremors, and alleviate the irresistible urge to move the legs associated with Restless Legs Syndrome.
Dosage by Body Weight
Dosage must be individualized and gradually titrated under strict medical supervision. For Parkinson's disease, the initial dose is typically 0.125 mg taken three times daily, slowly increased weekly. For Restless Legs Syndrome, it is usually taken once daily, 2 to 3 hours before bedtime. Do not discontinue suddenly as it may cause severe withdrawal symptoms.
- Body Weight
- Below 5 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Pramipexole is not recommended or approved for pediatric use.
- Body Weight
- 5-7 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Safety and efficacy have not been established in children.
- Body Weight
- 8-10 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Not suitable for pediatric patients.
- Body Weight
- 11-15 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Avoid use unless explicitly directed by a specialized pediatric neurologist.
- Body Weight
- 16-20 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Standard dosing is established only for adults; pediatric dosing is not routine.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not indicated | Not applicable | Pramipexole is not recommended or approved for pediatric use. |
| 5-7 kg | Not indicated | Not applicable | Safety and efficacy have not been established in children. |
| 8-10 kg | Not indicated | Not applicable | Not suitable for pediatric patients. |
| 11-15 kg | Not indicated | Not applicable | Avoid use unless explicitly directed by a specialized pediatric neurologist. |
| 16-20 kg | Not indicated | Not applicable | Standard dosing is established only for adults; pediatric dosing is not routine. |
Formulation
Purpose
Treatment of Parkinson's disease symptoms (stiffness, tremors, muscle spasms, and poor muscle control) and moderate-to-severe Restless Legs Syndrome (RLS).
Generic Name
PramipexoleScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.