Vitamin K Injection
Vitamin K injection contains phytonadione (vitamin K1), which is essential for the liver to synthesize blood clotting factors II (prothrombin), VII, IX, and X. It is a critical, life-saving medication routinely given to newborn infants to prevent severe, spontaneous bleeding.
Dosage by Body Weight
For newborn prophylaxis, a single intramuscular (IM) dose of 0.5 mg to 1 mg is given within 1 hour of birth. For older children and adults, dosing is highly individualized based on the indication, severity of bleeding, and coagulation parameters (PT/INR). Must be administered by a healthcare professional.
- Body Weight
- Below 5 kg
- Dose
- 0.5 mg to 1 mg
- Frequency
- Single dose
- Tracking Notes
- Standard newborn prophylactic dose given IM within 1 hour of birth. Premature infants weighing under 2.5 kg may receive a lower dose of 0.3 mg/kg to 0.5 mg.
- Body Weight
- 5-7 kg
- Dose
- As prescribed
- Frequency
- Individualized
- Tracking Notes
- Dosage is determined by a pediatrician based on the specific bleeding risk or clotting factors.
- Body Weight
- 8-10 kg
- Dose
- As prescribed
- Frequency
- Individualized
- Tracking Notes
- Dosage is determined by a pediatrician based on the specific bleeding risk or clotting factors.
- Body Weight
- 11-15 kg
- Dose
- As prescribed
- Frequency
- Individualized
- Tracking Notes
- Dose is carefully calculated based on PT/INR levels if treating deficiency or toxicity.
- Body Weight
- 16-20 kg
- Dose
- As prescribed
- Frequency
- Individualized
- Tracking Notes
- Dose is carefully calculated based on PT/INR levels if treating deficiency or toxicity.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 0.5 mg to 1 mg | Single dose | Standard newborn prophylactic dose given IM within 1 hour of birth. Premature infants weighing under 2.5 kg may receive a lower dose of 0.3 mg/kg to 0.5 mg. |
| 5-7 kg | As prescribed | Individualized | Dosage is determined by a pediatrician based on the specific bleeding risk or clotting factors. |
| 8-10 kg | As prescribed | Individualized | Dosage is determined by a pediatrician based on the specific bleeding risk or clotting factors. |
| 11-15 kg | As prescribed | Individualized | Dose is carefully calculated based on PT/INR levels if treating deficiency or toxicity. |
| 16-20 kg | As prescribed | Individualized | Dose is carefully calculated based on PT/INR levels if treating deficiency or toxicity. |
Formulation
Purpose
Prevention and treatment of vitamin K deficiency bleeding (VKDB) in newborns, and treatment of hypoprothrombinemia caused by anticoagulant overdose or dietary deficiency.
Generic Name
PhytonadioneBranded Drug Names
Vitamin K Injection is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.