Mephyton
Mephyton (phytonadione) is a synthetic lipid-soluble analog of vitamin K1. Vitamin K is an essential cofactor required for the hepatic synthesis of active blood clotting factors, including prothrombin (factor II), factor VII, factor IX, and factor X.
Dosage by Body Weight
Adult oral dosage typically ranges from 2.5 mg to 10 mg, up to 25 mg or more depending on the severity of the hypoprothrombinemia and response. Pediatric dosing is highly individualized, requires close medical monitoring, and is not standardly administered based on OTC body weight charts.
- Body Weight
- Below 5 kg
- Dose
- Strictly individualized
- Frequency
- As directed by specialist
- Tracking Notes
- Infants typically receive injectable phytonadione (Vitamin K1) immediately after birth. Oral tablets are not routinely used in this weight range.
- Body Weight
- 5-7 kg
- Dose
- Strictly individualized
- Frequency
- As directed by physician
- Tracking Notes
- Requires close hematological monitoring. Dose is determined based on INR and underlying cause of vitamin K deficiency.
- Body Weight
- 8-10 kg
- Dose
- Strictly individualized
- Frequency
- As directed by physician
- Tracking Notes
- Requires close hematological monitoring. Dose is determined based on INR and underlying cause of vitamin K deficiency.
- Body Weight
- 11-15 kg
- Dose
- Strictly individualized
- Frequency
- As directed by physician
- Tracking Notes
- Doses are tailored to the specific pediatric indication and coagulation profile. Do not self-administer.
- Body Weight
- 16-20 kg
- Dose
- Strictly individualized
- Frequency
- As directed by physician
- Tracking Notes
- Doses are tailored to the specific pediatric indication and coagulation profile. Do not self-administer.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Strictly individualized | As directed by specialist | Infants typically receive injectable phytonadione (Vitamin K1) immediately after birth. Oral tablets are not routinely used in this weight range. |
| 5-7 kg | Strictly individualized | As directed by physician | Requires close hematological monitoring. Dose is determined based on INR and underlying cause of vitamin K deficiency. |
| 8-10 kg | Strictly individualized | As directed by physician | Requires close hematological monitoring. Dose is determined based on INR and underlying cause of vitamin K deficiency. |
| 11-15 kg | Strictly individualized | As directed by physician | Doses are tailored to the specific pediatric indication and coagulation profile. Do not self-administer. |
| 16-20 kg | Strictly individualized | As directed by physician | Doses are tailored to the specific pediatric indication and coagulation profile. Do not self-administer. |
Formulation
Purpose
Used to treat coagulation disorders and hypoprothrombinemia caused by vitamin K deficiency or certain medications like anticoagulants (e.g., warfarin).
Generic Name
PhytonadioneScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.