Noctec
Noctec is a brand name for chloral hydrate, a sedative-hypnotic agent used primarily for short-term sedation and sleep induction. It is a Schedule IV controlled substance due to potential for abuse, physical dependence, and tolerance. Because of its narrow therapeutic index and the availability of safer alternatives, Noctec has been largely discontinued or restricted in many countries.
Dosage by Body Weight
Adult insomnia: Typical dose is 500 mg to 1000 mg taken 15 to 30 minutes before bedtime. Adult sedation: 250 mg three times daily after meals. Pediatric sedation: 25 mg to 50 mg per kg of body weight as a single dose, up to a maximum of 1000 mg per dose. Syrup forms should be diluted with water or fruit juice to prevent stomach upset.
- Body Weight
- Below 5 kg
- Dose
- Not routine / 25-50 mg/kg
- Frequency
- Single dose
- Tracking Notes
- Use with extreme caution in neonates and premature infants due to an immature liver's inability to metabolize active metabolites, leading to accumulation.
- Body Weight
- 5-7 kg
- Dose
- 125 mg to 350 mg
- Frequency
- Single dose
- Tracking Notes
- For pre-procedure sedation, administer approximately 30 minutes before the procedure. Must be monitored by a healthcare professional.
- Body Weight
- 8-10 kg
- Dose
- 200 mg to 500 mg
- Frequency
- Single dose
- Tracking Notes
- Monitor oxygen saturation and airway continuously during sedation.
- Body Weight
- 11-15 kg
- Dose
- 275 mg to 750 mg
- Frequency
- Single dose
- Tracking Notes
- Always dilute liquid formulations in water or juice to minimize gastric irritation.
- Body Weight
- 16-20 kg
- Dose
- 400 mg to 1000 mg
- Frequency
- Single dose
- Tracking Notes
- Do not exceed the maximum single pediatric sedation dose of 1000 mg (1 g).
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine / 25-50 mg/kg | Single dose | Use with extreme caution in neonates and premature infants due to an immature liver's inability to metabolize active metabolites, leading to accumulation. |
| 5-7 kg | 125 mg to 350 mg | Single dose | For pre-procedure sedation, administer approximately 30 minutes before the procedure. Must be monitored by a healthcare professional. |
| 8-10 kg | 200 mg to 500 mg | Single dose | Monitor oxygen saturation and airway continuously during sedation. |
| 11-15 kg | 275 mg to 750 mg | Single dose | Always dilute liquid formulations in water or juice to minimize gastric irritation. |
| 16-20 kg | 400 mg to 1000 mg | Single dose | Do not exceed the maximum single pediatric sedation dose of 1000 mg (1 g). |
Formulation
Purpose
Short-term treatment of insomnia, and as a sedative before medical, dental, or surgical procedures.
Generic Name
Chloral hydrateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.