Temazepam
Temazepam is an intermediate-acting benzodiazepine derivative. It functions as a central nervous system depressant by enhancing the inhibitory activity of gamma-aminobutyric acid (GABA) in the brain to facilitate sleep onset and maintenance. It is highly regulated due to risks of tolerance, dependence, abuse, and withdrawal symptoms, and is generally indicated for brief treatment periods of 7 to 10 days.
Dosage by Body Weight
The standard adult dose is 15 mg to 30 mg taken orally once daily at bedtime. For elderly, debilitated, or sensitive patients, a lower starting dose of 7.5 mg is recommended to minimize the risk of coordination loss, cognitive impairment, or oversedation. Use the lowest effective dose for the shortest duration necessary. Pediatric safety and efficacy have not been established.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness of temazepam have not been established in pediatric populations; contraindicated in infants.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Not recommended for pediatric use. Seek specialized medical advice for sleep disorders in children.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Not indicated for pediatric use due to risks of profound respiratory depression and cognitive impairment.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Do not administer to children unless explicitly prescribed and monitored by a specialist pediatric physician.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Do not administer to children unless explicitly prescribed and monitored by a specialist pediatric physician.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and effectiveness of temazepam have not been established in pediatric populations; contraindicated in infants. |
| 5-7 kg | Not recommended | N/A | Not recommended for pediatric use. Seek specialized medical advice for sleep disorders in children. |
| 8-10 kg | Not recommended | N/A | Not indicated for pediatric use due to risks of profound respiratory depression and cognitive impairment. |
| 11-15 kg | Not recommended | N/A | Do not administer to children unless explicitly prescribed and monitored by a specialist pediatric physician. |
| 16-20 kg | Not recommended | N/A | Do not administer to children unless explicitly prescribed and monitored by a specialist pediatric physician. |
Formulation
Purpose
Short-term treatment of insomnia (difficulty falling asleep, frequent night awakenings, or early morning awakenings).
Generic Name
TemazepamBranded Drug Names
Temazepam is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.