Ramelteon
Ramelteon is a selective melatonin receptor agonist that targets the MT1 and MT2 receptors in the suprachiasmatic nucleus, which regulates the natural sleep-wake cycle. Unlike traditional sedative-hypnotics, it does not bind to GABA receptors, which means it is not associated with abuse potential, tolerance, or physical dependence, and is not classified as a controlled substance.
Dosage by Body Weight
The recommended dose for adults is 8 mg taken orally once daily, within 30 minutes before going to bed. It should not be taken with or immediately after a high-fat meal, as this can delay its onset of action. It is not approved for pediatric use.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 5-7 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 8-10 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 11-15 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 16-20 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
Formulation
Purpose
Treatment of insomnia characterized by difficulty with sleep onset.
Generic Name
RamelteonBranded Drug Names
Ramelteon is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.