Nadolol
Nadolol is a non-selective beta-adrenergic receptor blocker (beta-blocker). It works by blocking the action of certain natural chemicals in the body, such as epinephrine, on the heart and blood vessels. This effect lowers the heart rate, blood pressure, and strain on the heart.
Dosage by Body Weight
For adults with hypertension, the typical starting dose is 40 mg orally once daily, which may be gradually increased up to 240-320 mg daily if needed. For angina, the typical starting dose is 40 mg once daily, titrated upward as required. Pediatric safety and effectiveness have not been well-established, and dosing must be individualized and supervised by a specialist.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established. Avoid use unless explicitly prescribed and monitored by a specialist.
- Body Weight
- 5-7 kg
- Dose
- Specialist determination only
- Frequency
- Once daily
- Tracking Notes
- Beta-blocker therapy in infants requires extreme caution and precise titration under pediatric cardiology supervision.
- Body Weight
- 8-10 kg
- Dose
- Specialist determination only
- Frequency
- Once daily
- Tracking Notes
- Usually calculated based on body surface area or mg/kg (e.g., 0.5 to 2 mg/kg/day) by a pediatric specialist.
- Body Weight
- 11-15 kg
- Dose
- Specialist determination only
- Frequency
- Once daily
- Tracking Notes
- Requires close monitoring of heart rate and blood pressure. Dose must be individualized.
- Body Weight
- 16-20 kg
- Dose
- Specialist determination only
- Frequency
- Once daily
- Tracking Notes
- Requires strict medical supervision. Do not abruptly discontinue therapy.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. Avoid use unless explicitly prescribed and monitored by a specialist. |
| 5-7 kg | Specialist determination only | Once daily | Beta-blocker therapy in infants requires extreme caution and precise titration under pediatric cardiology supervision. |
| 8-10 kg | Specialist determination only | Once daily | Usually calculated based on body surface area or mg/kg (e.g., 0.5 to 2 mg/kg/day) by a pediatric specialist. |
| 11-15 kg | Specialist determination only | Once daily | Requires close monitoring of heart rate and blood pressure. Dose must be individualized. |
| 16-20 kg | Specialist determination only | Once daily | Requires strict medical supervision. Do not abruptly discontinue therapy. |
Formulation
Purpose
Treatment of hypertension (high blood pressure) and management of angina pectoris (chest pain). It is also used off-label for migraine prophylaxis, portal hypertension, and certain cardiac arrhythmias.
Generic Name
NadololBranded Drug Names
Nadolol is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.