Myfortic
Myfortic contains mycophenolate sodium, an immunosuppressant agent that inhibits the enzyme inosine monophosphate dehydrogenase. This action blocks the de novo pathway of guanosine nucleotide synthesis, which selectively inhibits the proliferation of T and B lymphocytes, helping to prevent the rejection of transplanted kidneys.
Dosage by Body Weight
The standard adult dose is 720 mg taken orally twice daily (1440 mg daily dose) on an empty stomach, either 1 hour before or 2 hours after meals. Tablets must be swallowed whole and not crushed, chewed, or split to protect the enteric coating. Pediatric dosing is strictly determined by a specialist based on Body Surface Area (BSA).
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established for this weight range.
- Body Weight
- 5-7 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Dosing in pediatric patients is highly specialized and calculated based on Body Surface Area (BSA), not weight alone.
- Body Weight
- 8-10 kg
- Dose
- Specialist calculation required
- Frequency
- Twice daily
- Tracking Notes
- Pediatric dose is typically based on 400 mg/m² of Body Surface Area (BSA) twice daily, up to a maximum of 720 mg twice daily.
- Body Weight
- 11-15 kg
- Dose
- Specialist calculation required
- Frequency
- Twice daily
- Tracking Notes
- Dosed according to Body Surface Area (BSA). Must be prescribed and monitored by a transplant specialist.
- Body Weight
- 16-20 kg
- Dose
- Specialist calculation required
- Frequency
- Twice daily
- Tracking Notes
- Dosed according to Body Surface Area (BSA). Must be prescribed and monitored by a transplant specialist.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established for this weight range. |
| 5-7 kg | Not routine | Use only if prescribed | Dosing in pediatric patients is highly specialized and calculated based on Body Surface Area (BSA), not weight alone. |
| 8-10 kg | Specialist calculation required | Twice daily | Pediatric dose is typically based on 400 mg/m² of Body Surface Area (BSA) twice daily, up to a maximum of 720 mg twice daily. |
| 11-15 kg | Specialist calculation required | Twice daily | Dosed according to Body Surface Area (BSA). Must be prescribed and monitored by a transplant specialist. |
| 16-20 kg | Specialist calculation required | Twice daily | Dosed according to Body Surface Area (BSA). Must be prescribed and monitored by a transplant specialist. |
Formulation
Purpose
Prophylaxis of organ rejection in patients receiving allogeneic renal transplants, used in combination with cyclosporine and corticosteroids.
Generic Name
Mycophenolic acid (as mycophenolate sodium)Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.