Lucassin
Lucassin contains Terlipressin, a synthetic vasopressin analogue. It acts as a prodrug for lysine-vasopressin. It induces vasoconstriction of splanchnic and extrahepatic vessels, which lowers portal venous pressure and helps manage hepatorenal syndrome and variceal bleeding.
Dosage by Body Weight
For intravenous use only in a hospital setting under specialist supervision. Adults: Typically 1 to 2 mg IV initially, followed by 1 to 2 mg every 4 to 6 hours for bleeding varices. For hepatorenal syndrome, 0.5 mg to 2 mg IV every 6 hours.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness in pediatric patients have not been established.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
| 5-7 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
| 8-10 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
| 11-15 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
| 16-20 kg | Not recommended | N/A | Safety and effectiveness in pediatric patients have not been established. |
Formulation
InjectionPowder for solution for injection
Purpose
Treatment of hepatorenal syndrome (Type 1) and management of acute bleeding esophageal varices.
Generic Name
TerlipressinScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.