Leucovorin (Folinic Acid)
A reduced form of folic acid. In cancer treatment, it 'rescues' normal cells from the toxic effects of methotrexate.
Dosage by Body Weight
Dosing is highly specific to the chemotherapy protocol. For nutritional use: 5-15 mg daily.
- Body Weight
- Any weight
- Dose
- 5 mg to 15 mg
- Frequency
- Once daily
- Tracking Notes
- Strict timing is essential when used for methotrexate rescue.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Any weight | 5 mg to 15 mg | Once daily | Strict timing is essential when used for methotrexate rescue. |
Formulation
Purpose
Used to reduce the side effects of Methotrexate (rescue therapy) or to treat folate deficiency.
Generic Name
Folinic AcidBranded Drug Names
Leucovorin (Folinic Acid) is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONLeucovorin (Folinic Acid): Alcohol can increase liver strain, stomach irritation, or immune-related complications. Avoid alcohol unless your specialist allows it.
Pregnancy
CAUTIONLeucovorin (Folinic Acid): Use in pregnancy only under specialist advice because immune, cancer, or transplant treatment requires careful risk assessment.
Breast Feeding
CAUTIONLeucovorin (Folinic Acid): Breastfeeding may not be recommended with some immunosuppressive or chemotherapy medicines. Follow specialist advice.
Driving
CAUTIONLeucovorin (Folinic Acid): May cause dizziness, fatigue, nausea, or weakness. Avoid driving if affected.
Liver
CAUTIONLeucovorin (Folinic Acid): Can affect liver function and usually requires regular blood tests. Use only with specialist monitoring.
Kidney
CAUTIONLeucovorin (Folinic Acid): Kidney function may need close monitoring, particularly with calcineurin inhibitors or high-risk regimens.