Larinate
Larinate is an antimalarial medication containing Artesunate, an artemisinin derivative. It acts rapidly by killing the malaria parasites (schizonts) in the red blood cells. It is widely used in both oral and parenteral forms for treating malaria and is typically prescribed as part of an Artemisinin-based Combination Therapy (ACT) to minimize the development of drug resistance.
Dosage by Body Weight
Larinate should be taken exactly as directed by a physician. The duration and dose depend on the patient's body weight, age, and clinical severity. It is usually administered daily for 3 to 5 days, often in combination with a companion drug.
- Body Weight
- Below 5 kg
- Dose
- Not routinely recommended
- Frequency
- Use only under strict specialist supervision
- Tracking Notes
- Safety and efficacy in infants under 5 kg are not fully established. Consult a pediatrician immediately.
- Body Weight
- 5-7 kg
- Dose
- 12.5 mg to 25 mg
- Frequency
- Once daily for 3 days
- Tracking Notes
- Administer with food or milk. If the child vomits within 30 minutes of taking the dose, repeat the full dose.
- Body Weight
- 8-10 kg
- Dose
- 25 mg
- Frequency
- Once daily for 3 days
- Tracking Notes
- Ensure complete compliance with the full 3-day course to prevent relapse or parasite resistance.
- Body Weight
- 11-15 kg
- Dose
- 50 mg
- Frequency
- Once daily for 3 days
- Tracking Notes
- Monitor the child for common side effects such as dizziness, nausea, or headache.
- Body Weight
- 16-20 kg
- Dose
- 75 mg
- Frequency
- Once daily for 3 days
- Tracking Notes
- Can be administered as a whole tablet or dispersed in water if the child has difficulty swallowing.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routinely recommended | Use only under strict specialist supervision | Safety and efficacy in infants under 5 kg are not fully established. Consult a pediatrician immediately. |
| 5-7 kg | 12.5 mg to 25 mg | Once daily for 3 days | Administer with food or milk. If the child vomits within 30 minutes of taking the dose, repeat the full dose. |
| 8-10 kg | 25 mg | Once daily for 3 days | Ensure complete compliance with the full 3-day course to prevent relapse or parasite resistance. |
| 11-15 kg | 50 mg | Once daily for 3 days | Monitor the child for common side effects such as dizziness, nausea, or headache. |
| 16-20 kg | 75 mg | Once daily for 3 days | Can be administered as a whole tablet or dispersed in water if the child has difficulty swallowing. |
Formulation
Purpose
Treatment of acute, uncomplicated and severe malaria caused by Plasmodium falciparum, including chloroquine-resistant strains.
Generic Name
ArtesunateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.